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Mutations flanking the carbohydrate binding site of surfactant protein D confer antiviral activity for pandemic influenza A viruses.
Nikolaidis NM, White MR, Allen K, Tripathi S, Qi L, McDonald B, Taubenberger J, Seaton BA, McCormack FX, Crouch EC, Hartshorn KL. Nikolaidis NM, et al. Among authors: hartshorn kl. Am J Physiol Lung Cell Mol Physiol. 2014 Jun 1;306(11):L1036-44. doi: 10.1152/ajplung.00035.2014. Epub 2014 Apr 4. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24705721 Free PMC article.
Contemporary avian influenza A virus subtype H1, H6, H7, H10, and H15 hemagglutinin genes encode a mammalian virulence factor similar to the 1918 pandemic virus H1 hemagglutinin.
Qi L, Pujanauski LM, Davis AS, Schwartzman LM, Chertow DS, Baxter D, Scherler K, Hartshorn KL, Slemons RD, Walters KA, Kash JC, Taubenberger JK. Qi L, et al. Among authors: hartshorn kl. mBio. 2014 Nov 18;5(6):e02116. doi: 10.1128/mBio.02116-14. mBio. 2014. PMID: 25406382 Free PMC article.
Arginine-rich histones have strong antiviral activity for influenza A viruses.
Hoeksema M, Tripathi S, White M, Qi L, Taubenberger J, van Eijk M, Haagsman H, Hartshorn KL. Hoeksema M, et al. Among authors: hartshorn kl. Innate Immun. 2015 Oct;21(7):736-45. doi: 10.1177/1753425915593794. Epub 2015 Jul 2. Innate Immun. 2015. PMID: 26138524 Free PMC article.
171 results