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Aging, atherosclerosis, and IGF-1.
Higashi Y, Sukhanov S, Anwar A, Shai SY, Delafontaine P. Higashi Y, et al. Among authors: shai sy. J Gerontol A Biol Sci Med Sci. 2012 Jun;67(6):626-39. doi: 10.1093/gerona/gls102. Epub 2012 Apr 5. J Gerontol A Biol Sci Med Sci. 2012. PMID: 22491965 Free PMC article. Review.
Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA.
Blackstock CD, Higashi Y, Sukhanov S, Shai SY, Stefanovic B, Tabony AM, Yoshida T, Delafontaine P. Blackstock CD, et al. Among authors: shai sy. J Biol Chem. 2014 Mar 14;289(11):7264-74. doi: 10.1074/jbc.M113.518951. Epub 2014 Jan 27. J Biol Chem. 2014. PMID: 24469459 Free PMC article.
Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E-Deficient Mice.
Higashi Y, Sukhanov S, Shai SY, Danchuk S, Tang R, Snarski P, Li Z, Lobelle-Rich P, Wang M, Wang D, Yu H, Korthuis R, Delafontaine P. Higashi Y, et al. Among authors: shai sy. Circulation. 2016 Jun 7;133(23):2263-78. doi: 10.1161/CIRCULATIONAHA.116.021805. Epub 2016 May 6. Circulation. 2016. PMID: 27154724 Free PMC article.
SM22α (Smooth Muscle Protein 22-α) Promoter-Driven IGF1R (Insulin-Like Growth Factor 1 Receptor) Deficiency Promotes Atherosclerosis.
Sukhanov S, Higashi Y, Shai SY, Snarski P, Danchuk S, D'Ambra V, Tabony M, Woods TC, Hou X, Li Z, Ozoe A, Chandrasekar B, Takahashi SI, Delafontaine P. Sukhanov S, et al. Among authors: shai sy. Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2306-2317. doi: 10.1161/ATVBAHA.118.311134. Arterioscler Thromb Vasc Biol. 2018. PMID: 30354209 Free PMC article.
30 results