Ojima I - Search Results

1

Discovery of anti-TB agents that target the cell-division protein FtsZ.

Kumar K, Awasthi D, Berger WT, Tonge PJ, Slayden RA, Ojima I. Kumar K, et al. Among authors: ojima i. Future Med Chem. 2010 Aug;2(8):1305-23. doi: 10.4155/fmc.10.220. Future Med Chem. 2010. PMID: 21339840 Free PMC article. Review.

2

Recent advances in the medicinal chemistry of taxoids with novel beta-amino acid side chains.

Ojima I, Lin S, Wang T. Ojima I, et al. Curr Med Chem. 1999 Oct;6(10):927-54. Curr Med Chem. 1999. PMID: 10519906 Review.

3

New insights into drug resistance in cancer.

Ojima I, Ferlini C. Ojima I, et al. Chem Biol. 2003 Jul;10(7):583-4. doi: 10.1016/s1074-5521(03)00152-2. Chem Biol. 2003. PMID: 12890528 Free article.

4

Design, synthesis and structure-activity relationships of novel taxane-based multidrug resistance reversal agents.

Ojima I, Borella CP, Wu X, Bounaud PY, Oderda CF, Sturm M, Miller ML, Chakravarty S, Chen J, Huang Q, Pera P, Brooks TA, Baer MR, Bernacki RJ. Ojima I, et al. J Med Chem. 2005 Mar 24;48(6):2218-28. doi: 10.1021/jm049483y. J Med Chem. 2005. PMID: 15771464

5

Targeting FtsZ for antituberculosis drug discovery: noncytotoxic taxanes as novel antituberculosis agents.

Huang Q, Kirikae F, Kirikae T, Pepe A, Amin A, Respicio L, Slayden RA, Tonge PJ, Ojima I. Huang Q, et al. Among authors: ojima i. J Med Chem. 2006 Jan 26;49(2):463-6. doi: 10.1021/jm050920y. J Med Chem. 2006. PMID: 16420032 Free PMC article.

6

Recent advances in the new generation taxane anticancer agents.

Geney R, Chen J, Ojima I. Geney R, et al. Among authors: ojima i. Med Chem. 2005 Mar;1(2):125-39. doi: 10.2174/1573406053175292. Med Chem. 2005. PMID: 16787308 Review.

7

FtsZ: a novel target for tuberculosis drug discovery.

Huang Q, Tonge PJ, Slayden RA, Kirikae T, Ojima I. Huang Q, et al. Among authors: ojima i. Curr Top Med Chem. 2007;7(5):527-43. doi: 10.2174/156802607780059790. Curr Top Med Chem. 2007. PMID: 17346197 Review.

8

Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus.

Xu H, Sullivan TJ, Sekiguchi J, Kirikae T, Ojima I, Stratton CF, Mao W, Rock FL, Alley MR, Johnson F, Walker SG, Tonge PJ. Xu H, et al. Among authors: ojima i. Biochemistry. 2008 Apr 8;47(14):4228-36. doi: 10.1021/bi800023a. Epub 2008 Mar 13. Biochemistry. 2008. PMID: 18335995 Free PMC article.

9

Modern natural products chemistry and drug discovery.

Ojima I. Ojima I. J Med Chem. 2008 May 8;51(9):2587-8. doi: 10.1021/jm701291u. Epub 2008 Apr 5. J Med Chem. 2008. PMID: 18393400 No abstract available.

10

Design, synthesis, and biological evaluation of new-generation taxoids.

Ojima I, Chen J, Sun L, Borella CP, Wang T, Miller ML, Lin S, Geng X, Kuznetsova L, Qu C, Gallager D, Zhao X, Zanardi I, Xia S, Horwitz SB, Mallen-St Clair J, Guerriero JL, Bar-Sagi D, Veith JM, Pera P, Bernacki RJ. Ojima I, et al. J Med Chem. 2008 Jun 12;51(11):3203-21. doi: 10.1021/jm800086e. Epub 2008 May 9. J Med Chem. 2008. PMID: 18465846 Free PMC article.

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