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Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome.
Liu GH, Barkho BZ, Ruiz S, Diep D, Qu J, Yang SL, Panopoulos AD, Suzuki K, Kurian L, Walsh C, Thompson J, Boue S, Fung HL, Sancho-Martinez I, Zhang K, Yates J 3rd, Izpisua Belmonte JC. Liu GH, et al. Among authors: fung hl. Nature. 2011 Apr 14;472(7342):221-5. doi: 10.1038/nature09879. Epub 2011 Feb 23. Nature. 2011. PMID: 21346760 Free PMC article.
Somatic coding mutations in human induced pluripotent stem cells.
Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LS, Zhang K. Gore A, et al. Among authors: fung hl. Nature. 2011 Mar 3;471(7336):63-7. doi: 10.1038/nature09805. Nature. 2011. PMID: 21368825 Free PMC article.
Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs.
Liu GH, Suzuki K, Qu J, Sancho-Martinez I, Yi F, Li M, Kumar S, Nivet E, Kim J, Soligalla RD, Dubova I, Goebl A, Plongthongkum N, Fung HL, Zhang K, Loring JF, Laurent LC, Izpisua Belmonte JC. Liu GH, et al. Among authors: fung hl. Cell Stem Cell. 2011 Jun 3;8(6):688-94. doi: 10.1016/j.stem.2011.04.019. Epub 2011 May 19. Cell Stem Cell. 2011. PMID: 21596650 Free PMC article.
Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells.
Ruiz S, Diep D, Gore A, Panopoulos AD, Montserrat N, Plongthongkum N, Kumar S, Fung HL, Giorgetti A, Bilic J, Batchelder EM, Zaehres H, Kan NG, Schöler HR, Mercola M, Zhang K, Izpisua Belmonte JC. Ruiz S, et al. Among authors: fung hl. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16196-201. doi: 10.1073/pnas.1202352109. Epub 2012 Sep 18. Proc Natl Acad Sci U S A. 2012. PMID: 22991473 Free PMC article.
Human oocytes reprogram somatic cells to a pluripotent state.
Noggle S, Fung HL, Gore A, Martinez H, Satriani KC, Prosser R, Oum K, Paull D, Druckenmiller S, Freeby M, Greenberg E, Zhang K, Goland R, Sauer MV, Leibel RL, Egli D. Noggle S, et al. Among authors: fung hl. Nature. 2011 Oct 5;478(7367):70-5. doi: 10.1038/nature10397. Nature. 2011. PMID: 21979046
230 results