Notoya K - Search Results

1

Novel and potent calcium-sensing receptor antagonists: discovery of (5R)-N-[1-ethyl-1-(4-ethylphenyl)propyl]-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide monotosylate (TAK-075) as an orally active bone anabolic agent.

Yoshida M, Mori A, Morimoto S, Kotani E, Oka M, Notoya K, Makino H, Ono M, Shirasaki M, Tada N, Fujita H, Ban J, Ikeda Y, Kawamoto T, Goto M, Kimura H, Baba A, Yasuma T. Yoshida M, et al. Among authors: notoya k. Bioorg Med Chem. 2011 Mar 15;19(6):1881-94. doi: 10.1016/j.bmc.2011.02.001. Epub 2011 Feb 24. Bioorg Med Chem. 2011. PMID: 21353570

2

Synthesis of novel 2-benzothiopyran and 3-benzothiepin derivatives and their stimulatory effect on bone formation.

Oda T, Notoya K, Gotoh M, Taketomi S, Fujisawa Y, Makino H, Sohda T. Oda T, et al. Among authors: notoya k. J Med Chem. 1999 Feb 25;42(4):751-60. doi: 10.1021/jm980583b. J Med Chem. 1999. PMID: 10052981

3

Studies on disease-modifying antirheumatic drugs. III. Bone resorption inhibitory effects of ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1,2,4-triazol-1-ylmethyl) quinoline-3-carboxylate (TAK-603) and related compounds.

Baba A, Oda T, Taketomi S, Notoya K, Nishimura A, Makino H, Sohda T. Baba A, et al. Among authors: notoya k. Chem Pharm Bull (Tokyo). 1999 Mar;47(3):369-74. doi: 10.1248/cpb.47.369. Chem Pharm Bull (Tokyo). 1999. PMID: 10212387

4

Enhancement of osteogenesis in vitro by a novel osteoblast differentiation-promoting compound, TAK-778, partly through the expression of Msx2.

Gotoh M, Notoya K, Ienaga Y, Kawase M, Makino H. Gotoh M, et al. Among authors: notoya k. Eur J Pharmacol. 2002 Sep 6;451(1):19-25. doi: 10.1016/s0014-2999(02)02183-0. Eur J Pharmacol. 2002. PMID: 12223224

5

Enhancement of fracture repair in rats with streptozotocin-induced diabetes by a single injection of biodegradable microcapsules containing a bone formation stimulant, TAK-778.

Hoshino T, Muranishi H, Saito K, Notoya K, Makino H, Nagai H, Sohda T, Ogawa Y. Hoshino T, et al. Among authors: notoya k. J Biomed Mater Res. 2000 Sep 5;51(3):299-306. doi: 10.1002/1097-4636(20000905)51:3<299::aid-jbm2>3.0.co;2-8. J Biomed Mater Res. 2000. PMID: 10880070

6

Enhancement of osteogenesis in vitro and in vivo by a novel osteoblast differentiation promoting compound, TAK-778.

Notoya K, Nagai H, Oda T, Gotoh M, Hoshino T, Muranishi H, Taketomi S, Sohda T, Makino H. Notoya K, et al. J Pharmacol Exp Ther. 1999 Sep;290(3):1054-64. J Pharmacol Exp Ther. 1999. PMID: 10454478

7

Parathyroid hormone-activated volume-sensitive calcium influx pathways in mechanically loaded osteocytes.

Miyauchi A, Notoya K, Mikuni-Takagaki Y, Takagi Y, Goto M, Miki Y, Takano-Yamamoto T, Jinnai K, Takahashi K, Kumegawa M, Chihara K, Fujita T. Miyauchi A, et al. Among authors: notoya k. J Biol Chem. 2000 Feb 4;275(5):3335-42. doi: 10.1074/jbc.275.5.3335. J Biol Chem. 2000. PMID: 10652322 Free article.

8

Increase in femoral bone mass by ipriflavone alone and in combination with 1 alpha-hydroxyvitamin D3 in growing rats with skeletal unloading.

Notoya K, Yoshida K, Tsukuda R, Taketomi S, Tsuda M. Notoya K, et al. Calcif Tissue Int. 1996 Feb;58(2):88-94. doi: 10.1007/BF02529729. Calcif Tissue Int. 1996. PMID: 8998683

9

Advanced glycation end products enhance osteoclast-induced bone resorption in cultured mouse unfractionated bone cells and in rats implanted subcutaneously with devitalized bone particles.

Miyata T, Notoya K, Yoshida K, Horie K, Maeda K, Kurokawa K, Taketomi S. Miyata T, et al. Among authors: notoya k. J Am Soc Nephrol. 1997 Feb;8(2):260-70. doi: 10.1681/ASN.V82260. J Am Soc Nephrol. 1997. PMID: 9048345

10

Lack of effect of ipriflavone on osteoclast motility and bone resorption in in vitro and ex vivo studies.

Notoya K, Taketomi S, Tsuda M. Notoya K, et al. Calcif Tissue Int. 1993 Jul;53(1):71. doi: 10.1007/BF01352019. Calcif Tissue Int. 1993. PMID: 8348388 No abstract available.

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