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Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism.
Kansanen E, Bonacci G, Schopfer FJ, Kuosmanen SM, Tong KI, Leinonen H, Woodcock SR, Yamamoto M, Carlberg C, Ylä-Herttuala S, Freeman BA, Levonen AL. Kansanen E, et al. Among authors: schopfer fj. J Biol Chem. 2011 Apr 22;286(16):14019-27. doi: 10.1074/jbc.M110.190710. Epub 2011 Feb 25. J Biol Chem. 2011. PMID: 21357422 Free PMC article.
Fatty acid transduction of nitric oxide signaling: multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands.
Baker PR, Lin Y, Schopfer FJ, Woodcock SR, Groeger AL, Batthyany C, Sweeney S, Long MH, Iles KE, Baker LM, Branchaud BP, Chen YE, Freeman BA. Baker PR, et al. Among authors: schopfer fj. J Biol Chem. 2005 Dec 23;280(51):42464-75. doi: 10.1074/jbc.M504212200. Epub 2005 Oct 14. J Biol Chem. 2005. PMID: 16227625 Free PMC article.
118 results