Tong KI - Search Results

1

Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism.

Kansanen E, Bonacci G, Schopfer FJ, Kuosmanen SM, Tong KI, Leinonen H, Woodcock SR, Yamamoto M, Carlberg C, Ylä-Herttuala S, Freeman BA, Levonen AL. Kansanen E, et al. Among authors: tong ki. J Biol Chem. 2011 Apr 22;286(16):14019-27. doi: 10.1074/jbc.M110.190710. Epub 2011 Feb 25. J Biol Chem. 2011. PMID: 21357422 Free PMC article.

2

Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles.

Itoh K, Tong KI, Yamamoto M. Itoh K, et al. Among authors: tong ki. Free Radic Biol Med. 2004 May 15;36(10):1208-13. doi: 10.1016/j.freeradbiomed.2004.02.075. Free Radic Biol Med. 2004. PMID: 15110385 Review.

3

Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.

Tong KI, Kobayashi A, Katsuoka F, Yamamoto M. Tong KI, et al. Biol Chem. 2006 Oct-Nov;387(10-11):1311-20. doi: 10.1515/BC.2006.164. Biol Chem. 2006. PMID: 17081101 Review.

4

The critical role of nitric oxide signaling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response.

Fujii S, Sawa T, Ihara H, Tong KI, Ida T, Okamoto T, Ahtesham AK, Ishima Y, Motohashi H, Yamamoto M, Akaike T. Fujii S, et al. Among authors: tong ki. J Biol Chem. 2010 Jul 30;285(31):23970-84. doi: 10.1074/jbc.M110.145441. Epub 2010 May 24. J Biol Chem. 2010. PMID: 20498371 Free PMC article.

5

Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1.

Kobayashi A, Kang MI, Watai Y, Tong KI, Shibata T, Uchida K, Yamamoto M. Kobayashi A, et al. Among authors: tong ki. Mol Cell Biol. 2006 Jan;26(1):221-9. doi: 10.1128/MCB.26.1.221-229.2006. Mol Cell Biol. 2006. PMID: 16354693 Free PMC article.

6

Structural insights into the similar modes of Nrf2 transcription factor recognition by the cytoplasmic repressor Keap1.

Padmanabhan B, Tong KI, Kobayashi A, Yamamoto M, Yokoyama S. Padmanabhan B, et al. Among authors: tong ki. J Synchrotron Radiat. 2008 May;15(Pt 3):273-6. doi: 10.1107/S090904950705114X. Epub 2008 Apr 18. J Synchrotron Radiat. 2008. PMID: 18421157 Free PMC article.

7

Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model.

Tong KI, Katoh Y, Kusunoki H, Itoh K, Tanaka T, Yamamoto M. Tong KI, et al. Mol Cell Biol. 2006 Apr;26(8):2887-900. doi: 10.1128/MCB.26.8.2887-2900.2006. Mol Cell Biol. 2006. PMID: 16581765 Free PMC article.

8

Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.

Toyama T, Sumi D, Shinkai Y, Yasutake A, Taguchi K, Tong KI, Yamamoto M, Kumagai Y. Toyama T, et al. Among authors: tong ki. Biochem Biophys Res Commun. 2007 Nov 23;363(3):645-50. doi: 10.1016/j.bbrc.2007.09.017. Epub 2007 Sep 18. Biochem Biophys Res Commun. 2007. PMID: 17904103

9

Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome.

Katoh Y, Iida K, Kang MI, Kobayashi A, Mizukami M, Tong KI, McMahon M, Hayes JD, Itoh K, Yamamoto M. Katoh Y, et al. Among authors: tong ki. Arch Biochem Biophys. 2005 Jan 15;433(2):342-50. doi: 10.1016/j.abb.2004.10.012. Arch Biochem Biophys. 2005. PMID: 15581590 Review.

10

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.

Shibata T, Ohta T, Tong KI, Kokubu A, Odogawa R, Tsuta K, Asamura H, Yamamoto M, Hirohashi S. Shibata T, et al. Among authors: tong ki. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13568-73. doi: 10.1073/pnas.0806268105. Epub 2008 Aug 29. Proc Natl Acad Sci U S A. 2008. PMID: 18757741 Free PMC article.

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