Warne PH - Search Results

1

PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs.

Weigelt B, Warne PH, Downward J. Weigelt B, et al. Among authors: warne ph. Oncogene. 2011 Jul 21;30(29):3222-33. doi: 10.1038/onc.2011.42. Epub 2011 Feb 28. Oncogene. 2011. PMID: 21358673

2

PI3K pathway dependencies in endometrioid endometrial cancer cell lines.

Weigelt B, Warne PH, Lambros MB, Reis-Filho JS, Downward J. Weigelt B, et al. Among authors: warne ph. Clin Cancer Res. 2013 Jul 1;19(13):3533-44. doi: 10.1158/1078-0432.CCR-12-3815. Epub 2013 May 14. Clin Cancer Res. 2013. PMID: 23674493 Free PMC article.

3

Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos.

Buday L, Warne PH, Downward J. Buday L, et al. Among authors: warne ph. Oncogene. 1995 Oct 5;11(7):1327-31. Oncogene. 1995. PMID: 7478553

4

Networks of interaction of p120cbl and p130cas with Crk and Grb2 adaptor proteins.

Khwaja A, Hallberg B, Warne PH, Downward J. Khwaja A, et al. Among authors: warne ph. Oncogene. 1996 Jun 20;12(12):2491-8. Oncogene. 1996. PMID: 8700507

5

Rictor is a novel target of p70 S6 kinase-1.

Treins C, Warne PH, Magnuson MA, Pende M, Downward J. Treins C, et al. Among authors: warne ph. Oncogene. 2010 Feb 18;29(7):1003-16. doi: 10.1038/onc.2009.401. Epub 2009 Nov 23. Oncogene. 2010. PMID: 19935711

6

A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1.

Cully M, Genevet A, Warne P, Treins C, Liu T, Bastien J, Baum B, Tapon N, Leevers SJ, Downward J. Cully M, et al. Mol Cell Biol. 2010 Jan;30(2):481-95. doi: 10.1128/MCB.00688-09. Epub 2009 Nov 16. Mol Cell Biol. 2010. PMID: 19917724 Free PMC article.

7

Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

Swanton C, Marani M, Pardo O, Warne PH, Kelly G, Sahai E, Elustondo F, Chang J, Temple J, Ahmed AA, Brenton JD, Downward J, Nicke B. Swanton C, et al. Among authors: warne ph. Cancer Cell. 2007 Jun;11(6):498-512. doi: 10.1016/j.ccr.2007.04.011. Cancer Cell. 2007. PMID: 17560332 Free article.

8

Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies.

Steckel M, Molina-Arcas M, Weigelt B, Marani M, Warne PH, Kuznetsov H, Kelly G, Saunders B, Howell M, Downward J, Hancock DC. Steckel M, et al. Among authors: warne ph. Cell Res. 2012 Aug;22(8):1227-45. doi: 10.1038/cr.2012.82. Epub 2012 May 22. Cell Res. 2012. PMID: 22613949 Free PMC article.

9

Role of Shc in the activation of Ras in response to epidermal growth factor and nerve growth factor.

Basu T, Warne PH, Downward J. Basu T, et al. Among authors: warne ph. Oncogene. 1994 Dec;9(12):3483-91. Oncogene. 1994. PMID: 7970708

10

Phosphatidylinositol 3' kinase: one of the effectors of Ras.

Rodriguez-Viciana P, Marte BM, Warne PH, Downward J. Rodriguez-Viciana P, et al. Among authors: warne ph. Philos Trans R Soc Lond B Biol Sci. 1996 Feb 29;351(1336):225-31; discussion 231-2. doi: 10.1098/rstb.1996.0020. Philos Trans R Soc Lond B Biol Sci. 1996. PMID: 8650270 Review.

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