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222 results

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Low-dose naproxen interferes with the antiplatelet effects of aspirin in healthy subjects: recommendations to minimize the functional consequences.
Anzellotti P, Capone ML, Jeyam A, Tacconelli S, Bruno A, Tontodonati P, Di Francesco L, Grossi L, Renda G, Merciaro G, Di Gregorio P, Price TS, Garcia Rodriguez LA, Patrignani P. Anzellotti P, et al. Among authors: di gregorio p, di francesco l. Arthritis Rheum. 2011 Mar;63(3):850-9. doi: 10.1002/art.30175. Arthritis Rheum. 2011. PMID: 21360514 Free article. Clinical Trial.
Human pharmacology of naproxen sodium.
Capone ML, Tacconelli S, Sciulli MG, Anzellotti P, Di Francesco L, Merciaro G, Di Gregorio P, Patrignani P. Capone ML, et al. Among authors: di gregorio p, di francesco l. J Pharmacol Exp Ther. 2007 Aug;322(2):453-60. doi: 10.1124/jpet.107.122283. Epub 2007 May 1. J Pharmacol Exp Ther. 2007. PMID: 17473175 Clinical Trial.
De novo synthesis of cyclooxygenase-1 counteracts the suppression of platelet thromboxane biosynthesis by aspirin.
Evangelista V, Manarini S, Di Santo A, Capone ML, Ricciotti E, Di Francesco L, Tacconelli S, Sacchetti A, D'Angelo S, Scilimati A, Sciulli MG, Patrignani P. Evangelista V, et al. Among authors: di francesco l, di santo a. Circ Res. 2006 Mar 17;98(5):593-5. doi: 10.1161/01.RES.0000214553.37930.3e. Epub 2006 Feb 16. Circ Res. 2006. PMID: 16484611
Pharmacodynamic of cyclooxygenase inhibitors in humans.
Capone ML, Tacconelli S, Di Francesco L, Sacchetti A, Sciulli MG, Patrignani P. Capone ML, et al. Among authors: di francesco l. Prostaglandins Other Lipid Mediat. 2007 Jan;82(1-4):85-94. doi: 10.1016/j.prostaglandins.2006.05.019. Epub 2006 Jul 3. Prostaglandins Other Lipid Mediat. 2007. PMID: 17164136 Review.
Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro.
Bruno A, Di Francesco L, Coletta I, Mangano G, Alisi MA, Polenzani L, Milanese C, Anzellotti P, Ricciotti E, Dovizio M, Di Francesco A, Tacconelli S, Capone ML, Patrignani P. Bruno A, et al. Among authors: di francesco a, di francesco l. Biochem Pharmacol. 2010 Apr 1;79(7):974-81. doi: 10.1016/j.bcp.2009.11.011. Epub 2009 Nov 27. Biochem Pharmacol. 2010. PMID: 19925781
NCX 4040, a nitric oxide-donating aspirin, exerts anti-inflammatory effects through inhibition of I kappa B-alpha degradation in human monocytes.
Ricciotti E, Dovizio M, Di Francesco L, Anzellotti P, Salvatore T, Di Francesco A, Sciulli MG, Pistritto G, Monopoli A, Patrignani P. Ricciotti E, et al. Among authors: di francesco a, di francesco l. J Immunol. 2010 Feb 15;184(4):2140-7. doi: 10.4049/jimmunol.0903107. Epub 2010 Jan 11. J Immunol. 2010. PMID: 20065114
Effects of celecoxib on prostanoid biosynthesis and circulating angiogenesis proteins in familial adenomatous polyposis.
Dovizio M, Tacconelli S, Ricciotti E, Bruno A, Maier TJ, Anzellotti P, Di Francesco L, Sala P, Signoroni S, Bertario L, Dixon DA, Lawson JA, Steinhilber D, FitzGerald GA, Patrignani P. Dovizio M, et al. Among authors: di francesco l. J Pharmacol Exp Ther. 2012 Apr;341(1):242-50. doi: 10.1124/jpet.111.190785. Epub 2012 Jan 19. J Pharmacol Exp Ther. 2012. PMID: 22262921 Free PMC article.
Reduced Variability to Aspirin Antiplatelet Effect by the Coadministration of Statins in High-Risk Patients for Cardiovascular Disease.
Tacconelli S, Dovizio M, Di Francesco L, Meneguzzi A, D'Agostino I, Evangelista V, Manarini S, Capone ML, Grossi L, Porreca E, Di Febbo C, Bruno A, Ballerini P, Levantesi G, Fava C, Minuz P, Patrignani P. Tacconelli S, et al. Among authors: di febbo c, di francesco l. Clin Pharmacol Ther. 2018 Jul;104(1):111-119. doi: 10.1002/cpt.1075. Epub 2018 Apr 19. Clin Pharmacol Ther. 2018. PMID: 29574792
Reappraisal of the clinical pharmacology of low-dose aspirin by comparing novel direct and traditional indirect biomarkers of drug action.
Patrignani P, Tacconelli S, Piazuelo E, Di Francesco L, Dovizio M, Sostres C, Marcantoni E, Guillem-Llobat P, Del Boccio P, Zucchelli M, Patrono C, Lanas A. Patrignani P, et al. Among authors: di francesco l. J Thromb Haemost. 2014 Aug;12(8):1320-30. doi: 10.1111/jth.12637. Epub 2014 Jul 18. J Thromb Haemost. 2014. PMID: 24942808 Free article. Clinical Trial.
222 results