Söderlund H - Search Results

1

The testosterone binding mechanism of an antibody derived from a naïve human scFv library.

Niemi MH, Takkinen K, Amundsen LK, Söderlund H, Rouvinen J, Höyhtyä M. Niemi MH, et al. Among authors: soderlund h. J Mol Recognit. 2011 Mar-Apr;24(2):209-19. doi: 10.1002/jmr.1039. J Mol Recognit. 2011. PMID: 21360611

2

Structural insights into steroid hormone binding: the crystal structure of a recombinant anti-testosterone Fab fragment in free and testosterone-bound forms.

Valjakka J, Takkinenz K, Teerinen T, Söderlund H, Rouvinen J. Valjakka J, et al. Among authors: soderlund h. J Biol Chem. 2002 Feb 8;277(6):4183-90. doi: 10.1074/jbc.M105579200. Epub 2001 Nov 13. J Biol Chem. 2002. PMID: 11707437 Free article.

3

Crystal structure of an in vitro affinity- and specificity-matured anti-testosterone Fab in complex with testosterone. Improved affinity results from small structural changes within the variable domains.

Valjakka J, Hemminki A, Niemi S, Söderlund H, Takkinen K, Rouvinen J. Valjakka J, et al. Among authors: soderlund h. J Biol Chem. 2002 Nov 15;277(46):44021-7. doi: 10.1074/jbc.M208392200. Epub 2002 Aug 23. J Biol Chem. 2002. PMID: 12196551 Free article.

4

A structural insight into the molecular recognition of a (-)-Delta9-tetrahydrocannabinol and the development of a sensitive, one-step, homogeneous immunocomplex-based assay for its detection.

Niemi MH, Turunen L, Pulli T, Nevanen TK, Höyhtyä M, Söderlund H, Rouvinen J, Takkinen K. Niemi MH, et al. Among authors: soderlund h. J Mol Biol. 2010 Jul 23;400(4):803-14. doi: 10.1016/j.jmb.2010.05.048. Epub 2010 May 26. J Mol Biol. 2010. PMID: 20630472

5

Hevein-specific recombinant IgE antibodies from human single-chain antibody phage display libraries.

Laukkanen ML, Mäkinen-Kiljunen S, Isoherranen K, Haahtela T, Söderlund H, Takkinen K. Laukkanen ML, et al. Among authors: soderlund h. J Immunol Methods. 2003 Jul;278(1-2):271-81. doi: 10.1016/s0022-1759(03)00070-x. J Immunol Methods. 2003. PMID: 12957414

6

Molecular interactions between a recombinant IgE antibody and the beta-lactoglobulin allergen.

Niemi M, Jylhä S, Laukkanen ML, Söderlund H, Mäkinen-Kiljunen S, Kallio JM, Hakulinen N, Haahtela T, Takkinen K, Rouvinen J. Niemi M, et al. Among authors: soderlund h. Structure. 2007 Nov;15(11):1413-21. doi: 10.1016/j.str.2007.09.012. Structure. 2007. PMID: 17997967 Free article.

7

Automated panning and screening procedure on microplates for antibody generation from phage display libraries.

Turunen L, Takkinen K, Söderlund H, Pulli T. Turunen L, et al. Among authors: soderlund h. J Biomol Screen. 2009 Mar;14(3):282-93. doi: 10.1177/1087057108330113. Epub 2009 Feb 17. J Biomol Screen. 2009. PMID: 19224869

8

Selection of recombinant IgE antibodies binding the beta-lactoglobulin allergen in a conformation-dependent manner.

Jylhä S, Mäkinen-Kiljunen S, Haahtela T, Söderlund H, Takkinen K, Laukkanen ML. Jylhä S, et al. Among authors: soderlund h. J Immunol Methods. 2009 Oct 31;350(1-2):63-70. doi: 10.1016/j.jim.2009.07.007. Epub 2009 Jul 30. J Immunol Methods. 2009. PMID: 19647743

9

Transient dimers of allergens.

Rouvinen J, Jänis J, Laukkanen ML, Jylhä S, Niemi M, Päivinen T, Mäkinen-Kiljunen S, Haahtela T, Söderlund H, Takkinen K. Rouvinen J, et al. Among authors: soderlund h. PLoS One. 2010 Feb 5;5(2):e9037. doi: 10.1371/journal.pone.0009037. PLoS One. 2010. PMID: 20140203 Free PMC article.

10

Fine tuning of an anti-testosterone antibody binding site by stepwise optimisation of the CDRs.

Hemminki A, Niemi S, Hautoniemi L, Söderlund H, Takkinen K. Hemminki A, et al. Among authors: soderlund h. Immunotechnology. 1998 Jun;4(1):59-69. doi: 10.1016/s1380-2933(98)00002-5. Immunotechnology. 1998. PMID: 9661815

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