Diederich WE - Search Results

1

Stability-indicating HPLC assays for the determination of piritramide and droperidol in PCA solution.

Selbach S, Diederich WE, Fett S, Fründ D, Koch T, Eberhart LH. Selbach S, et al. Among authors: diederich we. J Clin Pharm Ther. 2011 Apr;36(2):161-5. doi: 10.1111/j.1365-2710.2010.01169.x. Epub 2010 Aug 13. J Clin Pharm Ther. 2011. PMID: 21366644

2

Frontiers in Medicinal Chemistry 2015: Meet the Experts of MedChem near the Cradle of Medicinal and Pharmaceutical Chemistry.

Wegscheid-Gerlach C, Gerber HD, Diederich WE. Wegscheid-Gerlach C, et al. Among authors: diederich we. ChemMedChem. 2015 Jul;10(7):1267-71. doi: 10.1002/cmdc.201500208. Epub 2015 Jun 2. ChemMedChem. 2015. PMID: 26038282

3

Native metabolomics identifies the rivulariapeptolide family of protease inhibitors.

Reher R, Aron AT, Fajtová P, Stincone P, Wagner B, Pérez-Lorente AI, Liu C, Shalom IYB, Bittremieux W, Wang M, Jeong K, Matos-Hernandez ML, Alexander KL, Caro-Diaz EJ, Naman CB, Scanlan JHW, Hochban PMM, Diederich WE, Molina-Santiago C, Romero D, Selim KA, Sass P, Brötz-Oesterhelt H, Hughes CC, Dorrestein PC, O'Donoghue AJ, Gerwick WH, Petras D. Reher R, et al. Among authors: diederich we. Nat Commun. 2022 Aug 8;13(1):4619. doi: 10.1038/s41467-022-32016-6. Nat Commun. 2022. PMID: 35941113 Free PMC article.

4

Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 protease.

Böttcher J, Blum A, Heine A, Diederich WE, Klebe G. Böttcher J, et al. Among authors: diederich we. J Mol Biol. 2008 Nov 7;383(2):347-57. doi: 10.1016/j.jmb.2008.07.062. Epub 2008 Jul 29. J Mol Biol. 2008. PMID: 18692068

5

Pyrrolidine derivatives as plasmepsin inhibitors: binding mode analysis assisted by molecular dynamics simulations of a highly flexible protein.

Luksch T, Blum A, Klee N, Diederich WE, Sotriffer CA, Klebe G. Luksch T, et al. Among authors: diederich we. ChemMedChem. 2010 Mar 1;5(3):443-54. doi: 10.1002/cmdc.200900452. ChemMedChem. 2010. PMID: 20112327

6

Development of improved PPARβ/δ inhibitors.

Toth PM, Naruhn S, Pape VF, Dörr SM, Klebe G, Müller R, Diederich WE. Toth PM, et al. Among authors: diederich we. ChemMedChem. 2012 Jan 2;7(1):159-70. doi: 10.1002/cmdc.201100408. Epub 2011 Oct 24. ChemMedChem. 2012. PMID: 22025402

7

The inverse agonist DG172 triggers a PPARβ/δ-independent myeloid lineage shift and promotes GM-CSF/IL-4-induced dendritic cell differentiation.

Lieber S, Scheer F, Finkernagel F, Meissner W, Giehl G, Brendel C, Diederich WE, Müller-Brüsselbach S, Müller R. Lieber S, et al. Among authors: diederich we. Mol Pharmacol. 2015 Feb;87(2):162-73. doi: 10.1124/mol.114.094672. Epub 2014 Nov 14. Mol Pharmacol. 2015. PMID: 25398837

8

KNOBLE: a knowledge-based approach for the design and synthesis of readily accessible small-molecule chemical probes to test protein binding.

Gerlach C, Münzel M, Baum B, Gerber HD, Craan T, Diederich WE, Klebe G. Gerlach C, et al. Among authors: diederich we. Angew Chem Int Ed Engl. 2007;46(47):9105-9. doi: 10.1002/anie.200703323. Angew Chem Int Ed Engl. 2007. PMID: 17955562 No abstract available.

9

Proteases of Plasmodium falciparum as potential drug targets and inhibitors thereof.

Wegscheid-Gerlach C, Gerber HD, Diederich WE. Wegscheid-Gerlach C, et al. Among authors: diederich we. Curr Top Med Chem. 2010;10(3):346-67. doi: 10.2174/156802610790725461. Curr Top Med Chem. 2010. PMID: 20166950 Review.

10

The medicinal chemistry of protease inhibitors.

Diederich WE, Wegscheid-Gerlach C. Diederich WE, et al. Curr Top Med Chem. 2010;10(3):231. doi: 10.2174/156802610790725443. Curr Top Med Chem. 2010. PMID: 20374196 No abstract available.

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