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The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells.
Baxter AE, Huang H, Giles JR, Chen Z, Wu JE, Drury S, Dalton K, Park SL, Torres L, Simone BW, Klapholz M, Ngiow SF, Freilich E, Manne S, Alcalde V, Ekshyyan V, Berger SL, Shi J, Jordan MS, Wherry EJ. Baxter AE, et al. Among authors: jordan ms. Immunity. 2023 Jun 13;56(6):1320-1340.e10. doi: 10.1016/j.immuni.2023.05.008. Immunity. 2023. PMID: 37315535 Free article.
The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR + CD8 + effector state and its deletion improves checkpoint blockade.
McClory SE, Bardhan O, Rome KS, Giles JR, Baxter AE, Xu L, Gimotty PA, Faryabi RB, Wherry EJ, Pear WS, Jordan MS. McClory SE, et al. Among authors: jordan ms. bioRxiv [Preprint]. 2023 Feb 16:2023.02.16.528833. doi: 10.1101/2023.02.16.528833. bioRxiv. 2023. Update in: Cell Rep. 2023 Aug 29;42(8):112905. doi: 10.1016/j.celrep.2023.112905. PMID: 36824931 Free PMC article. Updated. Preprint.
MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection.
Stelekati E, Cai Z, Manne S, Chen Z, Beltra JC, Buchness LA, Leng X, Ristin S, Nzingha K, Ekshyyan V, Niavi C, Abdel-Hakeem MS, Ali MA, Drury S, Lau CW, Gao Z, Ban Y, Zhou SK, Ansel KM, Kurachi M, Jordan MS, Villarino AV, Ngiow SF, Wherry EJ. Stelekati E, et al. Among authors: jordan ms. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2106083119. doi: 10.1073/pnas.2106083119. Epub 2022 Apr 21. Proc Natl Acad Sci U S A. 2022. PMID: 35446623 Free PMC article.
DNA Methylation in T-Cell Development and Differentiation.
Correa LO, Jordan MS, Carty SA. Correa LO, et al. Among authors: jordan ms. Crit Rev Immunol. 2020;40(2):135-156. doi: 10.1615/CritRevImmunol.2020033728. Crit Rev Immunol. 2020. PMID: 32749092 Free PMC article. Review.
CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival.
Utley A, Chavel C, Lightman S, Holling GA, Cooper J, Peng P, Liu W, Barwick BG, Gavile CM, Maguire O, Murray-Dupuis M, Rozanski C, Jordan MS, Kambayashi T, Olejniczak SH, Boise LH, Lee KP. Utley A, et al. Among authors: jordan ms. Cell Rep. 2020 Jun 23;31(12):107815. doi: 10.1016/j.celrep.2020.107815. Cell Rep. 2020. PMID: 32579940 Free PMC article.
62 results