Toyama T - Search Results

1

Isothiocyanates reduce mercury accumulation via an Nrf2-dependent mechanism during exposure of mice to methylmercury.

Toyama T, Shinkai Y, Yasutake A, Uchida K, Yamamoto M, Kumagai Y. Toyama T, et al. Environ Health Perspect. 2011 Aug;119(8):1117-22. doi: 10.1289/ehp.1003123. Epub 2011 Mar 7. Environ Health Perspect. 2011. PMID: 21382770 Free PMC article.

2

Activation of the Nrf2 pathway, but decreased gamma-glutamylcysteine synthetase heavy subunit chain levels and caspase-3-dependent apoptosis during exposure of primary mouse hepatocytes to diphenylarsinic acid.

Sumi D, Manji A, Shinkai Y, Toyama T, Kumagai Y. Sumi D, et al. Among authors: toyama t. Toxicol Appl Pharmacol. 2007 Sep 15;223(3):218-24. doi: 10.1016/j.taap.2007.06.001. Epub 2007 Jun 18. Toxicol Appl Pharmacol. 2007. PMID: 17628625

3

Downregulation of arginase II and renal apoptosis by inorganic mercury: overexpression of arginase II reduces its apoptosis.

Kanda H, Kikushima M, Homma-Takeda S, Sumi D, Endo A, Toyama T, Miura N, Naganuma A, Kumagai Y. Kanda H, et al. Among authors: toyama t. Arch Toxicol. 2008 Feb;82(2):67-73. doi: 10.1007/s00204-007-0244-z. Epub 2007 Sep 14. Arch Toxicol. 2008. PMID: 17874066

4

Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.

Toyama T, Sumi D, Shinkai Y, Yasutake A, Taguchi K, Tong KI, Yamamoto M, Kumagai Y. Toyama T, et al. Biochem Biophys Res Commun. 2007 Nov 23;363(3):645-50. doi: 10.1016/j.bbrc.2007.09.017. Epub 2007 Sep 18. Biochem Biophys Res Commun. 2007. PMID: 17904103

5

Reduction of arginase I activity and manganese levels in the liver during exposure of rats to methylmercury: a possible mechanism.

Kanda H, Sumi D, Endo A, Toyama T, Chen CL, Kikushima M, Kumagai Y. Kanda H, et al. Among authors: toyama t. Arch Toxicol. 2008 Nov;82(11):803-8. doi: 10.1007/s00204-008-0307-9. Epub 2008 May 17. Arch Toxicol. 2008. PMID: 18488197

6

Role of aquaporin 9 in cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes.

Shinkai Y, Sumi D, Toyama T, Kaji T, Kumagai Y. Shinkai Y, et al. Among authors: toyama t. Toxicol Appl Pharmacol. 2009 Jun 1;237(2):232-6. doi: 10.1016/j.taap.2009.03.014. Epub 2009 Mar 31. Toxicol Appl Pharmacol. 2009. PMID: 19341753

7

Carbon monoxide derived from heme oxygenase-2 mediates reduction of methylmercury toxicity in SH-SY5Y cells.

Toyama T, Shinkai Y, Sumi D, Kumagai Y. Toyama T, et al. Toxicol Appl Pharmacol. 2010 Nov 15;249(1):86-90. doi: 10.1016/j.taap.2010.08.021. Epub 2010 Aug 31. Toxicol Appl Pharmacol. 2010. PMID: 20807546

8

Detoxification of methylmercury by hydrogen sulfide-producing enzyme in Mammalian cells.

Yoshida E, Toyama T, Shinkai Y, Sawa T, Akaike T, Kumagai Y. Yoshida E, et al. Among authors: toyama t. Chem Res Toxicol. 2011 Oct 17;24(10):1633-5. doi: 10.1021/tx200394g. Epub 2011 Sep 30. Chem Res Toxicol. 2011. PMID: 21951228

9

DNA microarray analysis of human neuroblastoma SH-SY5Y cells exposed to methylmercury.

Toyama T, Yoshida E, Shinkai Y, Kumagai Y. Toyama T, et al. J Toxicol Sci. 2011;36(6):843-5. doi: 10.2131/jts.36.843. J Toxicol Sci. 2011. PMID: 22129749 Free article.

10

S-Mercuration of rat sorbitol dehydrogenase by methylmercury causes its aggregation and the release of the zinc ion from the active site.

Kanda H, Toyama T, Shinohara-Kanda A, Iwamatsu A, Shinkai Y, Kaji T, Kikushima M, Kumagai Y. Kanda H, et al. Among authors: toyama t. Arch Toxicol. 2012 Nov;86(11):1693-702. doi: 10.1007/s00204-012-0893-4. Epub 2012 Jun 30. Arch Toxicol. 2012. PMID: 22752181

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