Austin CA - Search Results

1

Green tea constituents (-)-epigallocatechin-3-gallate (EGCG) and gallic acid induce topoisomerase I- and topoisomerase II-DNA complexes in cells mediated by pyrogallol-induced hydrogen peroxide.

López-Lázaro M, Calderón-Montaño JM, Burgos-Morón E, Austin CA. López-Lázaro M, et al. Among authors: austin ca. Mutagenesis. 2011 Jul;26(4):489-98. doi: 10.1093/mutage/ger006. Epub 2011 Mar 7. Mutagenesis. 2011. PMID: 21382914

2

Expression, domain structure, and enzymatic properties of an active recombinant human DNA topoisomerase II beta.

Austin CA, Marsh KL, Wasserman RA, Willmore E, Sayer PJ, Wang JC, Fisher LM. Austin CA, et al. J Biol Chem. 1995 Jun 30;270(26):15739-46. doi: 10.1074/jbc.270.26.15739. J Biol Chem. 1995. PMID: 7797575 Free article.

3

Formation and longevity of idarubicin-induced DNA topoisomerase II cleavable complexes in K562 human leukaemia cells.

Willmore E, Errington F, Tilby MJ, Austin CA. Willmore E, et al. Among authors: austin ca. Biochem Pharmacol. 2002 May 15;63(10):1807-15. doi: 10.1016/s0006-2952(02)00920-6. Biochem Pharmacol. 2002. PMID: 12034365

4

Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients.

López-Lázaro M, Pastor N, Azrak SS, Ayuso MJ, Austin CA, Cortés F. López-Lázaro M, et al. Among authors: austin ca. J Nat Prod. 2005 Nov;68(11):1642-5. doi: 10.1021/np050226l. J Nat Prod. 2005. PMID: 16309315

5

Digitoxin, at concentrations commonly found in the plasma of cardiac patients, antagonizes etoposide and idarubicin activity in K562 leukemia cells.

López-Lázaro M, Pastor N, Azrak SS, Ayuso MJ, Cortés F, Austin CA. López-Lázaro M, et al. Among authors: austin ca. Leuk Res. 2006 Jul;30(7):895-8. doi: 10.1016/j.leukres.2005.11.005. Epub 2006 Jan 4. Leuk Res. 2006. PMID: 16387358

6

Cells lacking DNA topoisomerase II beta are resistant to genistein.

López-Lazaro M, Willmore E, Austin CA. López-Lazaro M, et al. Among authors: austin ca. J Nat Prod. 2007 May;70(5):763-7. doi: 10.1021/np060609z. Epub 2007 Apr 6. J Nat Prod. 2007. PMID: 17411092

7

Curcumin induces high levels of topoisomerase I- and II-DNA complexes in K562 leukemia cells.

López-Lázaro M, Willmore E, Jobson A, Gilroy KL, Curtis H, Padget K, Austin CA. López-Lázaro M, et al. Among authors: austin ca. J Nat Prod. 2007 Dec;70(12):1884-8. doi: 10.1021/np070332i. Epub 2007 Dec 13. J Nat Prod. 2007. PMID: 18076140

8

The impact of the human DNA topoisomerase II C-terminal domain on activity.

Meczes EL, Gilroy KL, West KL, Austin CA. Meczes EL, et al. Among authors: austin ca. PLoS One. 2008 Mar 12;3(3):e1754. doi: 10.1371/journal.pone.0001754. PLoS One. 2008. PMID: 18335031 Free PMC article.

9

Selenite induces topoisomerase I and II-DNA complexes in K562 leukemia cells.

López-Lázaro M, Willmore E, Elliott SL, Austin CA. López-Lázaro M, et al. Among authors: austin ca. Int J Cancer. 2008 Nov 1;123(9):2217-21. doi: 10.1002/ijc.23783. Int J Cancer. 2008. PMID: 18712718

10

The dietary flavonoids myricetin and fisetin act as dual inhibitors of DNA topoisomerases I and II in cells.

López-Lázaro M, Willmore E, Austin CA. López-Lázaro M, et al. Among authors: austin ca. Mutat Res. 2010 Feb;696(1):41-7. doi: 10.1016/j.mrgentox.2009.12.010. Epub 2009 Dec 16. Mutat Res. 2010. PMID: 20025993

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