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Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations.
Pedemonte N, Tomati V, Sondo E, Caci E, Millo E, Armirotti A, Damonte G, Zegarra-Moran O, Galietta LJ. Pedemonte N, et al. Among authors: millo e. J Biol Chem. 2011 Apr 29;286(17):15215-26. doi: 10.1074/jbc.M110.184267. Epub 2011 Mar 7. J Biol Chem. 2011. PMID: 21383017 Free PMC article.
Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.
Pesce E, Bellotti M, Liessi N, Guariento S, Damonte G, Cichero E, Galatini A, Salis A, Gianotti A, Pedemonte N, Zegarra-Moran O, Fossa P, Galietta LJ, Millo E. Pesce E, et al. Among authors: millo e. Eur J Med Chem. 2015 Jun 24;99:14-35. doi: 10.1016/j.ejmech.2015.05.030. Epub 2015 May 28. Eur J Med Chem. 2015. PMID: 26041577
Speeding Up the Identification of Cystic Fibrosis Transmembrane Conductance Regulator-Targeted Drugs: An Approach Based on Bioinformatics Strategies and Surface Plasmon Resonance.
Rusnati M, Sala D, Orro A, Bugatti A, Trombetti G, Cichero E, Urbinati C, Di Somma M, Millo E, Galietta LJV, Milanesi L, Fossa P, D'Ursi P. Rusnati M, et al. Among authors: millo e. Molecules. 2018 Jan 8;23(1):120. doi: 10.3390/molecules23010120. Molecules. 2018. PMID: 29316712 Free PMC article.
Journey on VX-809-Based Hybrid Derivatives towards Drug-like F508del-CFTR Correctors: From Molecular Modeling to Chemical Synthesis and Biological Assays.
Parodi A, Righetti G, Pesce E, Salis A, Tomati V, Pastorino C, Tasso B, Benvenuti M, Damonte G, Pedemonte N, Cichero E, Millo E. Parodi A, et al. Among authors: millo e. Pharmaceuticals (Basel). 2022 Feb 23;15(3):274. doi: 10.3390/ph15030274. Pharmaceuticals (Basel). 2022. PMID: 35337072 Free PMC article.
111 results