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The GIP receptor activates futile calcium cycling in white adipose tissue to increase energy expenditure and drive weight loss in mice.
Yu X, Chen S, Funcke JB, Straub LG, Pirro V, Emont MP, Droz BA, Collins KA, Joung C, Pearson MJ, James CM, Babu GJ, Efthymiou V, Vernon A, Patti ME, An YA, Rosen ED, Coghlan MP, Samms RJ, Scherer PE, Kusminski CM. Yu X, et al. Among authors: pearson mj. Cell Metab. 2025 Jan 7;37(1):187-204.e7. doi: 10.1016/j.cmet.2024.11.003. Epub 2024 Dec 5. Cell Metab. 2025. PMID: 39642881
Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity.
Zhang T, Yu W, Cheng X, Yeung J, Ahumada V, Norris PC, Pearson MJ, Yang X, van Deursen W, Halcovich C, Nassar A, Vesely MD, Zhang Y, Zhang JP, Ji L, Flies DB, Liu L, Langermann S, LaRochelle WJ, Humphrey R, Zhao D, Zhang Q, Zhang J, Gu R, Schalper KA, Sanmamed MF, Chen L. Zhang T, et al. Among authors: pearson mj. Sci Immunol. 2024 Apr 26;9(94):eadh2334. doi: 10.1126/sciimmunol.adh2334. Epub 2024 Apr 26. Sci Immunol. 2024. PMID: 38669316
126 results