Beadle JR - Search Results

1

Antiproliferative property of hexadecyloxypropyl 9-[2-(phosphonomethoxy) ethyl] guanine (HDP-PMEG) for unwanted ocular proliferation.

Hou J, Li Y, Zhou Z, Valiaeva N, Beadle JR, Hostetler K, Freeman WR, Hu DN, Chen H, Cheng L. Hou J, et al. Among authors: beadle jr. Mol Vis. 2011 Mar 2;17:627-37. Mol Vis. 2011. PMID: 21386925 Free PMC article.

2

Intravitreal toxicology and therapeutic efficacy of the carboxymethyl ester of the 1-O-octadecyl-sn-glycerol-3-phosphonoformate (ODG-PFA-O-Me), a novel lipid antiviral prodrug for intraocular drug delivery.

Cheng L, Hostetler KY, Gardner MF, Avila CP Jr, Bergeron-Lynn G, Keefe KS, Beadle JR, Wiley CA, Freeman WR. Cheng L, et al. Among authors: beadle jr. J Ocul Pharmacol Ther. 1999 Aug;15(4):363-77. doi: 10.1089/jop.1999.15.363. J Ocul Pharmacol Ther. 1999. PMID: 10463875

3

Intravitreal toxicology and duration of efficacy of a novel antiviral lipid prodrug of ganciclovir in liposome formulation.

Cheng L, Hostetler KY, Chaidhawangul S, Gardner MF, Beadle JR, Keefe KS, Bergeron-Lynn G, Severson GM, Soules KA, Mueller AJ, Freeman WR. Cheng L, et al. Among authors: beadle jr. Invest Ophthalmol Vis Sci. 2000 May;41(6):1523-32. Invest Ophthalmol Vis Sci. 2000. PMID: 10798672

4

Treatment or prevention of herpes simplex virus retinitis with intravitreally injectable crystalline 1-O-hexadecylpropanediol-3-phospho-ganciclovir.

Cheng L, Hostetler KY, Chaidhawangul S, Gardner MF, Beadle JR, Toyoguchi M, Bergeron-Lynn G, Freeman WR. Cheng L, et al. Among authors: beadle jr. Invest Ophthalmol Vis Sci. 2002 Feb;43(2):515-21. Invest Ophthalmol Vis Sci. 2002. PMID: 11818399

5

Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir.

Kern ER, Hartline C, Harden E, Keith K, Rodriguez N, Beadle JR, Hostetler KY. Kern ER, et al. Among authors: beadle jr. Antimicrob Agents Chemother. 2002 Apr;46(4):991-5. doi: 10.1128/AAC.46.4.991-995.2002. Antimicrob Agents Chemother. 2002. PMID: 11897580 Free PMC article.

6

Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro.

Beadle JR, Hartline C, Aldern KA, Rodriguez N, Harden E, Kern ER, Hostetler KY. Beadle JR, et al. Antimicrob Agents Chemother. 2002 Aug;46(8):2381-6. doi: 10.1128/AAC.46.8.2381-2386.2002. Antimicrob Agents Chemother. 2002. PMID: 12121908 Free PMC article.

7

Ganciclovir release rates in vitreous from different formulations of 1-O-hexadecylpropanediol-3-phospho-ganciclovir.

Cheng L, Hostetler KY, Toyoguchi M, Beadle JR, Rodanant N, Gardner MF, Aldern KA, Bergeron-Lynn G, Freeman WR. Cheng L, et al. Among authors: beadle jr. J Ocul Pharmacol Ther. 2003 Apr;19(2):161-9. doi: 10.1089/108076803321637690. J Ocul Pharmacol Ther. 2003. PMID: 12804061

8

Oral treatment of cowpox and vaccinia virus infections in mice with ether lipid esters of cidofovir.

Quenelle DC, Collins DJ, Wan WB, Beadle JR, Hostetler KY, Kern ER. Quenelle DC, et al. Among authors: beadle jr. Antimicrob Agents Chemother. 2004 Feb;48(2):404-12. doi: 10.1128/AAC.48.2.404-412.2004. Antimicrob Agents Chemother. 2004. PMID: 14742188 Free PMC article.

9

Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model.

Buller RM, Owens G, Schriewer J, Melman L, Beadle JR, Hostetler KY. Buller RM, et al. Among authors: beadle jr. Virology. 2004 Jan 20;318(2):474-81. doi: 10.1016/j.virol.2003.11.015. Virology. 2004. PMID: 14972516 Free article.

10

Inhibitory activity of alkoxyalkyl and alkyl esters of cidofovir and cyclic cidofovir against orthopoxvirus replication in vitro.

Keith KA, Wan WB, Ciesla SL, Beadle JR, Hostetler KY, Kern ER. Keith KA, et al. Among authors: beadle jr. Antimicrob Agents Chemother. 2004 May;48(5):1869-71. doi: 10.1128/AAC.48.5.1869-1871.2004. Antimicrob Agents Chemother. 2004. PMID: 15105146 Free PMC article.

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