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Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure.
De Jonghe BC, Hayes MR, Banno R, Skibicka KP, Zimmer DJ, Bowen KA, Leichner TM, Alhadeff AL, Kanoski SE, Cyr NE, Nillni EA, Grill HJ, Bence KK. De Jonghe BC, et al. Among authors: cyr ne. Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1002-11. doi: 10.1152/ajpendo.00639.2010. Epub 2011 Mar 15. Am J Physiol Endocrinol Metab. 2011. PMID: 21406615 Free PMC article.
Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide α-MSH and the processing enzyme CPE production in diet-induced obese male rats.
Cyr NE, Steger JS, Toorie AM, Yang JZ, Stuart R, Nillni EA. Cyr NE, et al. Endocrinology. 2014 Jul;155(7):2423-35. doi: 10.1210/en.2013-1998. Epub 2014 Apr 28. Endocrinology. 2014. Retraction in: Endocrinology. 2014 Dec;155(12):5042. doi: 10.1210/en.2014-1867 PMID: 24773342 Free PMC article. Retracted.
Mechanisms by which the orexigen NPY regulates anorexigenic α-MSH and TRH.
Cyr NE, Toorie AM, Steger JS, Sochat MM, Hyner S, Perello M, Stuart R, Nillni EA. Cyr NE, et al. Am J Physiol Endocrinol Metab. 2013 Mar 15;304(6):E640-50. doi: 10.1152/ajpendo.00448.2012. Epub 2013 Jan 15. Am J Physiol Endocrinol Metab. 2013. PMID: 23321476 Free PMC article.
The Nutrient and Energy Sensor Sirt1 Regulates the Hypothalamic-Pituitary-Adrenal (HPA) Axis by Altering the Production of the Prohormone Convertase 2 (PC2) Essential in the Maturation of Corticotropin-releasing Hormone (CRH) from Its Prohormone in Male Rats.
Toorie AM, Cyr NE, Steger JS, Beckman R, Farah G, Nillni EA. Toorie AM, et al. Among authors: cyr ne. J Biol Chem. 2016 Mar 11;291(11):5844-5859. doi: 10.1074/jbc.M115.675264. Epub 2016 Jan 11. J Biol Chem. 2016. PMID: 26755731 Free PMC article.
26 results