Li Y - Search Results

1

Total synthesis of novel D-ring-modified triptolide analogues: structure-cytotoxic activity relationship studies on the D-ring of triptolide.

Zhou B, Li X, Tang H, Miao Z, Feng H, Li Y. Zhou B, et al. Among authors: li y, li x. Org Biomol Chem. 2011 May 7;9(9):3176-9. doi: 10.1039/c0ob01239d. Epub 2011 Mar 15. Org Biomol Chem. 2011. PMID: 21409265

2

Synthesis of six-membered spirocyclic oxindoles with five consecutive stereocenters in an asymmetric organocatalytic one-pot Michael/Michael/aldol addition sequence.

Zhou B, Yang Y, Shi J, Luo Z, Li Y. Zhou B, et al. Among authors: li y. J Org Chem. 2013 Apr 5;78(7):2897-907. doi: 10.1021/jo302655u. Epub 2013 Mar 8. J Org Chem. 2013. PMID: 23469872

3

Design, synthesis and structure-activity relationships studies on the D ring of the natural product triptolide.

Xu H, Tang H, Feng H, Li Y. Xu H, et al. Among authors: li y. ChemMedChem. 2014 Feb;9(2):290-5. doi: 10.1002/cmdc.201300409. Epub 2013 Dec 11. ChemMedChem. 2014. PMID: 24339424

4

Design, synthesis and anticancer activity evaluation of novel C14 heterocycle substituted epi-triptolide.

Xu H, Tang H, Feng H, Li Y. Xu H, et al. Among authors: li y. Eur J Med Chem. 2014 Feb 12;73:46-55. doi: 10.1016/j.ejmech.2013.11.044. Epub 2013 Dec 14. Eur J Med Chem. 2014. PMID: 24378709

5

Divergent total synthesis of triptolide, triptonide, tripdiolide, 16-hydroxytriptolide, and their analogues.

Xu H, Tang H, Feng H, Li Y. Xu H, et al. Among authors: li y. J Org Chem. 2014 Nov 7;79(21):10110-22. doi: 10.1021/jo501744j. Epub 2014 Oct 24. J Org Chem. 2014. PMID: 25296383

6

Semisynthesis of triptolide analogues: effect of B-ring substituents on cytotoxic activities.

Xu H, Chen Y, Tang H, Feng H, Li Y. Xu H, et al. Among authors: li y. Bioorg Med Chem Lett. 2014 Dec 15;24(24):5671-5674. doi: 10.1016/j.bmcl.2014.10.069. Epub 2014 Oct 29. Bioorg Med Chem Lett. 2014. PMID: 25467158

7

Access to Six- and Seven-Membered 1,7-Fused Indolines via Rh(III)-Catalyzed Redox-Neutral C7-Selective C-H Functionalization of Indolines with Alkynes and Alkenes.

Wang X, Tang H, Feng H, Li Y, Yang Y, Zhou B. Wang X, et al. Among authors: li y. J Org Chem. 2015 Jun 19;80(12):6238-49. doi: 10.1021/acs.joc.5b00684. Epub 2015 Jun 1. J Org Chem. 2015. PMID: 25989195

8

Synthesis and biological evaluation of novel triptolide analogues for anticancer activity.

Zhou B, Miao Z, Deng G, Ding J, Yang Y, Feng H, Li Y. Zhou B, et al. Among authors: li y. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6217-21. doi: 10.1016/j.bmcl.2010.08.106. Epub 2010 Aug 26. Bioorg Med Chem Lett. 2010. PMID: 20833543

9

Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms.

Zhou ZL, Yang YX, Ding J, Li YC, Miao ZH. Zhou ZL, et al. Nat Prod Rep. 2012 Apr;29(4):457-75. doi: 10.1039/c2np00088a. Epub 2012 Jan 23. Nat Prod Rep. 2012. PMID: 22270059 Review.

10

Design and synthesis of novel C14-hydroxyl substituted triptolide derivatives as potential selective antitumor agents.

Li Z, Zhou ZL, Miao ZH, Lin LP, Feng HJ, Tong LJ, Ding J, Li YC. Li Z, et al. J Med Chem. 2009 Aug 27;52(16):5115-23. doi: 10.1021/jm900342g. J Med Chem. 2009. PMID: 19637874

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