Simpson EH - Search Results

1

Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophrenia.

Simpson EH, Kellendonk C, Ward RD, Richards V, Lipatova O, Fairhurst S, Kandel ER, Balsam PD. Simpson EH, et al. Biol Psychiatry. 2011 May 15;69(10):928-35. doi: 10.1016/j.biopsych.2011.01.012. Epub 2011 Mar 16. Biol Psychiatry. 2011. PMID: 21414604 Free PMC article.

2

Using conditional mutagenesis to study the brain.

Morozov A, Kellendonk C, Simpson E, Tronche F. Morozov A, et al. Biol Psychiatry. 2003 Dec 1;54(11):1125-33. doi: 10.1016/s0006-3223(03)00467-0. Biol Psychiatry. 2003. PMID: 14643079 Review.

3

Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors.

Huang YY, Simpson E, Kellendonk C, Kandel ER. Huang YY, et al. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3236-41. doi: 10.1073/pnas.0308280101. Epub 2004 Feb 23. Proc Natl Acad Sci U S A. 2004. PMID: 14981263 Free PMC article.

4

Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning.

Kellendonk C, Simpson EH, Polan HJ, Malleret G, Vronskaya S, Winiger V, Moore H, Kandel ER. Kellendonk C, et al. Among authors: simpson eh. Neuron. 2006 Feb 16;49(4):603-15. doi: 10.1016/j.neuron.2006.01.023. Neuron. 2006. PMID: 16476668 Free article.

5

DRD2 C957T polymorphism interacts with the COMT Val158Met polymorphism in human working memory ability.

Xu H, Kellendonk CB, Simpson EH, Keilp JG, Bruder GE, Polan HJ, Kandel ER, Gilliam TC. Xu H, et al. Among authors: simpson eh. Schizophr Res. 2007 Feb;90(1-3):104-7. doi: 10.1016/j.schres.2006.10.001. Epub 2006 Nov 17. Schizophr Res. 2007. PMID: 17113268

6

Transient overexpression of striatal D2 receptors impairs operant motivation and interval timing.

Drew MR, Simpson EH, Kellendonk C, Herzberg WG, Lipatova O, Fairhurst S, Kandel ER, Malapani C, Balsam PD. Drew MR, et al. Among authors: simpson eh. J Neurosci. 2007 Jul 18;27(29):7731-9. doi: 10.1523/JNEUROSCI.1736-07.2007. J Neurosci. 2007. PMID: 17634367 Free PMC article.

7

Transient and selective overexpression of D2 receptors in the striatum causes persistent deficits in conditional associative learning.

Bach ME, Simpson EH, Kahn L, Marshall JJ, Kandel ER, Kellendonk C. Bach ME, et al. Among authors: simpson eh. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):16027-32. doi: 10.1073/pnas.0807746105. Epub 2008 Oct 2. Proc Natl Acad Sci U S A. 2008. PMID: 18832466 Free PMC article.

8

Modeling cognitive endophenotypes of schizophrenia in mice.

Kellendonk C, Simpson EH, Kandel ER. Kellendonk C, et al. Among authors: simpson eh. Trends Neurosci. 2009 Jun;32(6):347-58. doi: 10.1016/j.tins.2009.02.003. Epub 2009 May 4. Trends Neurosci. 2009. PMID: 19409625 Free PMC article. Review.

9

Impaired timing precision produced by striatal D2 receptor overexpression is mediated by cognitive and motivational deficits.

Ward RD, Kellendonk C, Simpson EH, Lipatova O, Drew MR, Fairhurst S, Kandel ER, Balsam PD. Ward RD, et al. Among authors: simpson eh. Behav Neurosci. 2009 Aug;123(4):720-30. doi: 10.1037/a0016503. Behav Neurosci. 2009. PMID: 19634929 Free PMC article.

10

A possible role for the striatum in the pathogenesis of the cognitive symptoms of schizophrenia.

Simpson EH, Kellendonk C, Kandel E. Simpson EH, et al. Neuron. 2010 Mar 11;65(5):585-96. doi: 10.1016/j.neuron.2010.02.014. Neuron. 2010. PMID: 20223196 Free PMC article. Review.

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