Kocinsky HS - Search Results

1

NHERF2 is necessary for basal activity, second messenger inhibition, and LPA stimulation of NHE3 in mouse distal ileum.

Murtazina R, Kovbasnjuk O, Chen TE, Zachos NC, Chen Y, Kocinsky HS, Hogema BM, Seidler U, de Jonge HR, Donowitz M. Murtazina R, et al. Among authors: kocinsky hs. Am J Physiol Cell Physiol. 2011 Jul;301(1):C126-36. doi: 10.1152/ajpcell.00311.2010. Epub 2011 Mar 23. Am J Physiol Cell Physiol. 2011. PMID: 21430287 Free PMC article.

2

Cyclic GMP kinase II (cGKII) inhibits NHE3 by altering its trafficking and phosphorylating NHE3 at three required sites: identification of a multifunctional phosphorylation site.

Chen T, Kocinsky HS, Cha B, Murtazina R, Yang J, Tse CM, Singh V, Cole R, Aronson PS, de Jonge H, Sarker R, Donowitz M. Chen T, et al. Among authors: kocinsky hs. J Biol Chem. 2015 Jan 23;290(4):1952-65. doi: 10.1074/jbc.M114.590174. Epub 2014 Dec 5. J Biol Chem. 2015. PMID: 25480791 Free PMC article.

3

NHE3 phosphorylation at serines 552 and 605 does not directly affect NHE3 activity.

Kocinsky HS, Dynia DW, Wang T, Aronson PS. Kocinsky HS, et al. Am J Physiol Renal Physiol. 2007 Jul;293(1):F212-8. doi: 10.1152/ajprenal.00042.2007. Epub 2007 Apr 4. Am J Physiol Renal Physiol. 2007. PMID: 17409282 Free article.

4

Ezrin is required for the functional regulation of the epithelial sodium proton exchanger, NHE3.

Hayashi H, Tamura A, Krishnan D, Tsukita S, Suzuki Y, Kocinsky HS, Aronson PS, Orlowski J, Grinstein S, Alexander RT. Hayashi H, et al. Among authors: kocinsky hs. PLoS One. 2013;8(2):e55623. doi: 10.1371/journal.pone.0055623. Epub 2013 Feb 6. PLoS One. 2013. PMID: 23405179 Free PMC article.

5

Use of phospho-specific antibodies to determine the phosphorylation of endogenous Na+/H+ exchanger NHE3 at PKA consensus sites.

Kocinsky HS, Girardi AC, Biemesderfer D, Nguyen T, Mentone S, Orlowski J, Aronson PS. Kocinsky HS, et al. Am J Physiol Renal Physiol. 2005 Aug;289(2):F249-58. doi: 10.1152/ajprenal.00082.2004. Epub 2005 Feb 1. Am J Physiol Renal Physiol. 2005. PMID: 15687252 Free article.

6

NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase.

Dynia DW, Steinmetz AG, Kocinsky HS. Dynia DW, et al. Among authors: kocinsky hs. Am J Physiol Renal Physiol. 2010 Mar;298(3):F745-53. doi: 10.1152/ajprenal.00182.2009. Epub 2009 Dec 16. Am J Physiol Renal Physiol. 2010. PMID: 20015946 Free PMC article.

7

Membrane curvature alters the activation kinetics of the epithelial Na+/H+ exchanger, NHE3.

Alexander RT, Malevanets A, Durkan AM, Kocinsky HS, Aronson PS, Orlowski J, Grinstein S. Alexander RT, et al. Among authors: kocinsky hs. J Biol Chem. 2007 Mar 9;282(10):7376-84. doi: 10.1074/jbc.M608557200. Epub 2007 Jan 11. J Biol Chem. 2007. PMID: 17218318 Free article.

8

Effects of K+-deficient diets with and without NaCl supplementation on Na+, K+, and H2O transporters' abundance along the nephron.

Nguyen MT, Yang LE, Fletcher NK, Lee DH, Kocinsky H, Bachmann S, Delpire E, McDonough AA. Nguyen MT, et al. Am J Physiol Renal Physiol. 2012 Jul 1;303(1):F92-104. doi: 10.1152/ajprenal.00032.2012. Epub 2012 Apr 11. Am J Physiol Renal Physiol. 2012. PMID: 22496411 Free PMC article.

9

A phase I open-label study to investigate the potential drug-drug interaction between single-dose dacomitinib and steady-state paroxetine in healthy volunteers.

Ruiz-Garcia A, Giri N, LaBadie RR, Ni G, Boutros T, Richie N, Kocinsky HS, Checchio TM, Bello CL. Ruiz-Garcia A, et al. Among authors: kocinsky hs. J Clin Pharmacol. 2014 May;54(5):555-62. doi: 10.1002/jcph.243. Epub 2013 Dec 17. J Clin Pharmacol. 2014. PMID: 24293056 Clinical Trial.

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