Oppermann U - Search Results

1

Structural basis of fumarate hydratase deficiency.

Picaud S, Kavanagh KL, Yue WW, Lee WH, Muller-Knapp S, Gileadi O, Sacchettini J, Oppermann U. Picaud S, et al. Among authors: oppermann u. J Inherit Metab Dis. 2011 Jun;34(3):671-6. doi: 10.1007/s10545-011-9294-8. Epub 2011 Mar 29. J Inherit Metab Dis. 2011. PMID: 21445611 Free PMC article.

2

High-throughput structural biology of metabolic enzymes and its impact on human diseases.

Yue WW, Oppermann U. Yue WW, et al. Among authors: oppermann u. J Inherit Metab Dis. 2011 Jun;34(3):575-81. doi: 10.1007/s10545-011-9296-6. Epub 2011 Feb 22. J Inherit Metab Dis. 2011. PMID: 21340633 Review.

3

A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency.

Shafqat N, Kavanagh KL, Sass JO, Christensen E, Fukao T, Lee WH, Oppermann U, Yue WW. Shafqat N, et al. Among authors: oppermann u. J Inherit Metab Dis. 2013 Nov;36(6):983-7. doi: 10.1007/s10545-013-9589-z. Epub 2013 Feb 19. J Inherit Metab Dis. 2013. PMID: 23420214 Free PMC article.

4

Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity.

Lukacik P, Keller B, Bunkoczi G, Kavanagh KL, Lee WH, Adamski J, Oppermann U. Lukacik P, et al. Among authors: oppermann u. Biochem J. 2007 Mar 15;402(3):419-27. doi: 10.1042/BJ20061319. Biochem J. 2007. PMID: 17067289 Free PMC article.

5

Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria.

Johansson C, Kavanagh KL, Gileadi O, Oppermann U. Johansson C, et al. Among authors: oppermann u. J Biol Chem. 2007 Feb 2;282(5):3077-82. doi: 10.1074/jbc.M608179200. Epub 2006 Nov 22. J Biol Chem. 2007. PMID: 17121859 Free article.

6

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.

Ng SS, Kavanagh KL, McDonough MA, Butler D, Pilka ES, Lienard BM, Bray JE, Savitsky P, Gileadi O, von Delft F, Rose NR, Offer J, Scheinost JC, Borowski T, Sundstrom M, Schofield CJ, Oppermann U. Ng SS, et al. Among authors: oppermann u. Nature. 2007 Jul 5;448(7149):87-91. doi: 10.1038/nature05971. Epub 2007 Jun 24. Nature. 2007. PMID: 17589501

7

Structure-activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4.

Lee WH, Lukacik P, Guo K, Ugochukwu E, Kavanagh KL, Marsden B, Oppermann U. Lee WH, et al. Among authors: oppermann u. Mol Cell Endocrinol. 2009 Mar 25;301(1-2):199-204. doi: 10.1016/j.mce.2008.09.042. Epub 2008 Oct 22. Mol Cell Endocrinol. 2009. PMID: 19013211

8

Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A.

Kochan G, Pilka ES, von Delft F, Oppermann U, Yue WW. Kochan G, et al. Among authors: oppermann u. J Mol Biol. 2009 May 22;388(5):997-1008. doi: 10.1016/j.jmb.2009.03.064. Epub 2009 Apr 1. J Mol Biol. 2009. PMID: 19345228

9

Crystal structure of human carbonic anhydrase-related protein VIII reveals the basis for catalytic silencing.

Picaud SS, Muniz JR, Kramm A, Pilka ES, Kochan G, Oppermann U, Yue WW. Picaud SS, et al. Among authors: oppermann u. Proteins. 2009 Aug 1;76(2):507-11. doi: 10.1002/prot.22411. Proteins. 2009. PMID: 19360879 No abstract available.

10

Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases.

Bunkoczi G, Misquitta S, Wu X, Lee WH, Rojkova A, Kochan G, Kavanagh KL, Oppermann U, Smith S. Bunkoczi G, et al. Among authors: oppermann u. Chem Biol. 2009 Jun 26;16(6):667-75. doi: 10.1016/j.chembiol.2009.04.011. Chem Biol. 2009. PMID: 19549604 Free PMC article.

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