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306 results

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Page 1
Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain.
Borsook D, Upadhyay J, Klimas M, Schwarz AJ, Coimbra A, Baumgartner R, George E, Potter WZ, Large T, Bleakman D, Evelhoch J, Iyengar S, Becerra L, Hargreaves RJ. Borsook D, et al. Among authors: hargreaves rj. Drug Discov Today. 2012 Sep;17(17-18):964-73. doi: 10.1016/j.drudis.2012.05.004. Epub 2012 May 10. Drug Discov Today. 2012. PMID: 22579743 Review.
A role for fMRI in optimizing CNS drug development.
Borsook D, Becerra L, Hargreaves R. Borsook D, et al. Among authors: hargreaves r. Nat Rev Drug Discov. 2006 May;5(5):411-24. doi: 10.1038/nrd2027. Nat Rev Drug Discov. 2006. PMID: 16604100 Review.
Brain imaging in migraine research.
Borsook D, Hargreaves R. Borsook D, et al. Among authors: hargreaves r. Headache. 2010 Oct;50(9):1523-7. doi: 10.1111/j.1526-4610.2010.01761.x. Headache. 2010. PMID: 20958298 Review.
A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #2: protocol optimization and best practices.
Schwarz AJ, Becerra L, Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Evelhoch J, Hargreaves R, Robertson B, Iyengar S, Tauscher J, Bleakman D, Borsook D. Schwarz AJ, et al. Among authors: hargreaves r. Drug Discov Today. 2011 Aug;16(15-16):671-82. doi: 10.1016/j.drudis.2011.03.011. Epub 2011 Apr 6. Drug Discov Today. 2011. PMID: 21477664 Review.
A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #1: processes and requirements.
Schwarz AJ, Becerra L, Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Evelhoch J, Hargreaves R, Robertson B, Iyengar S, Tauscher J, Bleakman D, Borsook D. Schwarz AJ, et al. Among authors: hargreaves r. Drug Discov Today. 2011 Jul;16(13-14):583-93. doi: 10.1016/j.drudis.2011.05.006. Epub 2011 May 24. Drug Discov Today. 2011. PMID: 21635967 Review.
Imaging drugs with and without clinical analgesic efficacy.
Upadhyay J, Anderson J, Schwarz AJ, Coimbra A, Baumgartner R, Pendse G, George E, Nutile L, Wallin D, Bishop J, Neni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D. Upadhyay J, et al. Among authors: hargreaves r. Neuropsychopharmacology. 2011 Dec;36(13):2659-73. doi: 10.1038/npp.2011.156. Epub 2011 Aug 17. Neuropsychopharmacology. 2011. PMID: 21849979 Free PMC article. Clinical Trial.
306 results