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Pyrimethamine (2,4-diamino-5-p-chlorophenyl-6-ethylpyrimidine) induces apoptosis of freshly isolated human T lymphocytes, bypassing CD95/Fas molecule but involving its intrinsic pathway.
Pierdominici M, Giammarioli AM, Gambardella L, De Felice M, Quinti I, Iacobini M, Carbonari M, Malorni W, Giovannetti A. Pierdominici M, et al. J Pharmacol Exp Ther. 2005 Dec;315(3):1046-57. doi: 10.1124/jpet.105.086736. Epub 2005 Sep 12. J Pharmacol Exp Ther. 2005. PMID: 16157660
Unravelling the complexity of T cell abnormalities in common variable immunodeficiency.
Giovannetti A, Pierdominici M, Mazzetta F, Marziali M, Renzi C, Mileo AM, De Felice M, Mora B, Esposito A, Carello R, Pizzuti A, Paggi MG, Paganelli R, Malorni W, Aiuti F. Giovannetti A, et al. Among authors: pierdominici m. J Immunol. 2007 Mar 15;178(6):3932-43. doi: 10.4049/jimmunol.178.6.3932. J Immunol. 2007. PMID: 17339494 Clinical Trial.
Progressive derangement of the T cell compartment in a case of Evans syndrome.
Giovannetti A, Pierdominici M, Esposito A, Cagliuso M, Stifano G, Giammarioli AM, Maselli A, Malorni W, Salsano F, Aiuti F. Giovannetti A, et al. Among authors: pierdominici m. Int Arch Allergy Immunol. 2008;145(3):258-67. doi: 10.1159/000109295. Epub 2007 Oct 5. Int Arch Allergy Immunol. 2008. PMID: 17921676
Estrogen receptor profiles in human peripheral blood lymphocytes.
Pierdominici M, Maselli A, Colasanti T, Giammarioli AM, Delunardo F, Vacirca D, Sanchez M, Giovannetti A, Malorni W, Ortona E. Pierdominici M, et al. Immunol Lett. 2010 Aug 16;132(1-2):79-85. doi: 10.1016/j.imlet.2010.06.003. Epub 2010 Jun 11. Immunol Lett. 2010. PMID: 20542061
Analyses of T cell phenotype and function reveal an altered T cell homeostasis in systemic sclerosis. Correlations with disease severity and phenotypes.
Giovannetti A, Rosato E, Renzi C, Maselli A, Gambardella L, Giammarioli AM, Palange P, Paoletti P, Pisarri S, Salsano F, Malorni W, Pierdominici M. Giovannetti A, et al. Among authors: pierdominici m. Clin Immunol. 2010 Oct;137(1):122-33. doi: 10.1016/j.clim.2010.06.004. Epub 2010 Jun 26. Clin Immunol. 2010. PMID: 20580318
87 results