Hunt DK - Search Results

1

ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding.

Dunlop EA, Hunt DK, Acosta-Jaquez HA, Fingar DC, Tee AR. Dunlop EA, et al. Among authors: hunt dk. Autophagy. 2011 Jul;7(7):737-47. doi: 10.4161/auto.7.7.15491. Epub 2011 Jul 1. Autophagy. 2011. PMID: 21460630 Free PMC article.

2

Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine.

Johnson CE, Hunt DK, Wiltshire M, Herbert TP, Sampson JR, Errington RJ, Davies DM, Tee AR. Johnson CE, et al. Among authors: hunt dk. Mol Oncol. 2015 Mar;9(3):675-88. doi: 10.1016/j.molonc.2014.11.005. Epub 2014 Nov 22. Mol Oncol. 2015. PMID: 25498902 Free PMC article.

3

Massively parallel combination screen reveals small molecule sensitization of antibiotic-resistant Gram-negative ESKAPE pathogens.

Tse MW, Zhu M, Peters B, Hamami E, Chen J, Davis KP, Nitz S, Weller J, Warrier T, Hunt DK, Morales Y, Kawate T, Gaulin JL, Come JH, Hernandez-Bird J, Huo W, Neisewander I, Kiessling LL, Hung DT, Mecsas J, Aldridge BB, Isberg RR, Blainey PC. Tse MW, et al. Among authors: hunt dk. bioRxiv [Preprint]. 2024 Mar 26:2024.03.26.586803. doi: 10.1101/2024.03.26.586803. bioRxiv. 2024. PMID: 38585790 Free PMC article. Preprint.

4

Territory and population attributes affect Florida scrub-jay fecundity in fire-adapted ecosystems.

Breininger DR, Stolen ED, Carter GM, Legare SA, Payne WV, Breininger DJ, Lyon JE, Schumann CD, Hunt DK. Breininger DR, et al. Among authors: hunt dk. Ecol Evol. 2023 Jan 15;13(1):e9704. doi: 10.1002/ece3.9704. eCollection 2023 Jan. Ecol Evol. 2023. PMID: 36687801 Free PMC article.

5

Preclinical Development of Pentamidine Analogs Identifies a Potent and Nontoxic Antibiotic Adjuvant.

MacNair CR, Farha MA, Serrano-Wu MH, Lee KK, Hubbard B, Côté JP, Carfrae LA, Tu MM, Gaulin JL, Hunt DK, Hung DT, Brown ED. MacNair CR, et al. Among authors: hunt dk. ACS Infect Dis. 2022 Apr 8;8(4):768-777. doi: 10.1021/acsinfecdis.1c00482. Epub 2022 Mar 23. ACS Infect Dis. 2022. PMID: 35319198

6

Modeling vegetation community responses to sea-level rise on Barrier Island systems: A case study on the Cape Canaveral Barrier Island complex, Florida, USA.

Foster TE, Stolen ED, Hall CR, Schaub R, Duncan BW, Hunt DK, Drese JH. Foster TE, et al. Among authors: hunt dk. PLoS One. 2017 Aug 10;12(8):e0182605. doi: 10.1371/journal.pone.0182605. eCollection 2017. PLoS One. 2017. PMID: 28796807 Free PMC article.

7

Heterocyclyl tetracyclines. 2. 7-Methoxy-8-pyrrolidinyltetracyclines: discovery of TP-2758, a potent, orally efficacious antimicrobial against Gram-negative pathogens.

Sun C, Deng Y, Hunt DK, Fyfe C, Chen CL, Clark RB, Grossman TH, Sutcliffe JA, Xiao XY. Sun C, et al. Among authors: hunt dk. J Antibiot (Tokyo). 2018 Feb;71(2):287-297. doi: 10.1038/ja.2017.86. Epub 2017 Jul 26. J Antibiot (Tokyo). 2018. PMID: 28743974

8

Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa.

Deng Y, Sun C, Hunt DK, Fyfe C, Chen CL, Grossman TH, Sutcliffe JA, Xiao XY. Deng Y, et al. Among authors: hunt dk. J Med Chem. 2017 Mar 23;60(6):2498-2512. doi: 10.1021/acs.jmedchem.6b01903. Epub 2017 Mar 15. J Med Chem. 2017. PMID: 28248499

9

Design, Synthesis, and Biological Evaluation of Hexacyclic Tetracyclines as Potent, Broad Spectrum Antibacterial Agents.

Sun C, Hunt DK, Chen CL, Deng Y, He M, Clark RB, Fyfe C, Grossman TH, Sutcliffe JA, Xiao XY. Sun C, et al. Among authors: hunt dk. J Med Chem. 2015 Jun 11;58(11):4703-12. doi: 10.1021/acs.jmedchem.5b00262. Epub 2015 May 20. J Med Chem. 2015. PMID: 25927406

10

Synthesis and biological evaluation of 8-aminomethyltetracycline derivatives as novel antibacterial agents.

Clark RB, He M, Deng Y, Sun C, Chen CL, Hunt DK, O'Brien WJ, Fyfe C, Grossman TH, Sutcliffe JA, Achorn C, Hogan PC, Katz CE, Niu J, Zhang WY, Zhu Z, Ronn M, Xiao XY. Clark RB, et al. Among authors: hunt dk. J Med Chem. 2013 Oct 24;56(20):8112-38. doi: 10.1021/jm401211t. Epub 2013 Oct 3. J Med Chem. 2013. PMID: 24047201

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