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The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB.
Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP. Schneider M, et al. Among authors: zimmermann ag. Nat Immunol. 2012 Sep;13(9):823-31. doi: 10.1038/ni.2378. Epub 2012 Aug 5. Nat Immunol. 2012. PMID: 22863753 Free PMC article.
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways.
Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP. Allen IC, et al. Among authors: zimmermann ag. Immunity. 2011 Jun 24;34(6):854-65. doi: 10.1016/j.immuni.2011.03.026. Immunity. 2011. PMID: 21703540 Free PMC article.
NLRX1 is a regulator of mitochondrial antiviral immunity.
Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, Accavitti-Loper MA, Madden VJ, Sun L, Ye Z, Lich JD, Heise MT, Chen Z, Ting JP. Moore CB, et al. Among authors: zimmermann ag. Nature. 2008 Jan 31;451(7178):573-7. doi: 10.1038/nature06501. Epub 2008 Jan 16. Nature. 2008. PMID: 18200010
Conventional murine gene targeting.
Zimmermann AG, Sun Y. Zimmermann AG, et al. Methods Mol Biol. 2013;1031:1-18. doi: 10.1007/978-1-62703-481-4_1. Methods Mol Biol. 2013. PMID: 23824881
48 results