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Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis.
Yang DS, Stavrides P, Mohan PS, Kaushik S, Kumar A, Ohno M, Schmidt SD, Wesson DW, Bandyopadhyay U, Jiang Y, Pawlik M, Peterhoff CM, Yang AJ, Wilson DA, St George-Hyslop P, Westaway D, Mathews PM, Levy E, Cuervo AM, Nixon RA. Yang DS, et al. Among authors: kaushik s. Autophagy. 2011 Jul;7(7):788-9. doi: 10.4161/auto.7.7.15596. Epub 2011 Jul 1. Autophagy. 2011. PMID: 21464620 Free PMC article.
Consequences of the selective blockage of chaperone-mediated autophagy.
Massey AC, Kaushik S, Sovak G, Kiffin R, Cuervo AM. Massey AC, et al. Among authors: kaushik s. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5805-10. doi: 10.1073/pnas.0507436103. Epub 2006 Apr 3. Proc Natl Acad Sci U S A. 2006. PMID: 16585521 Free PMC article.
Lysosomal chat maintains the balance.
Massey AC, Kaushik S, Cuervo AM. Massey AC, et al. Among authors: kaushik s. Autophagy. 2006 Oct-Dec;2(4):325-7. doi: 10.4161/auto.3090. Epub 2006 Oct 13. Autophagy. 2006. PMID: 16874078 Review.
Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy.
Martinez-Vicente M, Talloczy Z, Kaushik S, Massey AC, Mazzulli J, Mosharov EV, Hodara R, Fredenburg R, Wu DC, Follenzi A, Dauer W, Przedborski S, Ischiropoulos H, Lansbury PT, Sulzer D, Cuervo AM. Martinez-Vicente M, et al. Among authors: kaushik s. J Clin Invest. 2008 Feb;118(2):777-88. doi: 10.1172/JCI32806. J Clin Invest. 2008. PMID: 18172548 Free PMC article.
Chaperone-mediated autophagy.
Kaushik S, Cuervo AM. Kaushik S, et al. Methods Mol Biol. 2008;445:227-44. doi: 10.1007/978-1-59745-157-4_15. Methods Mol Biol. 2008. PMID: 18425454 Free PMC article.
1,269 results