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Page 1
Pathogenic T cell responses against aquaporin 4.
Pohl M, Fischer MT, Mader S, Schanda K, Kitic M, Sharma R, Wimmer I, Misu T, Fujihara K, Reindl M, Lassmann H, Bradl M. Pohl M, et al. Among authors: kitic m. Acta Neuropathol. 2011 Jul;122(1):21-34. doi: 10.1007/s00401-011-0824-0. Epub 2011 Apr 6. Acta Neuropathol. 2011. PMID: 21468722 Free PMC article.
T cell-activation in neuromyelitis optica lesions plays a role in their formation.
Pohl M, Kawakami N, Kitic M, Bauer J, Martins R, Fischer MT, Machado-Santos J, Mader S, Ellwart JW, Misu T, Fujihara K, Wekerle H, Reindl M, Lassmann H, Bradl M. Pohl M, et al. Among authors: kitic m. Acta Neuropathol Commun. 2013 Dec 24;1:85. doi: 10.1186/2051-5960-1-85. Acta Neuropathol Commun. 2013. PMID: 24367907 Free PMC article.
NG2 plays a role in neuroinflammation but is not expressed by immune cells.
Kitic M, Karram K, Israel N, Yogev N, Lacher SM, Tang Y, Yigit H, Bauer J, Wanke F, Knezovic A, Trotter J, Kurschus FC, Waisman A. Kitic M, et al. Acta Neuropathol. 2017 Aug;134(2):325-327. doi: 10.1007/s00401-017-1735-5. Epub 2017 May 31. Acta Neuropathol. 2017. PMID: 28567522 No abstract available.
Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood-brain barrier.
Hauptmann J, Johann L, Marini F, Kitic M, Colombo E, Mufazalov IA, Krueger M, Karram K, Moos S, Wanke F, Kurschus FC, Klein M, Cardoso S, Strauß J, Bolisetty S, Lühder F, Schwaninger M, Binder H, Bechman I, Bopp T, Agarwal A, Soares MP, Regen T, Waisman A. Hauptmann J, et al. Among authors: kitic m. Acta Neuropathol. 2020 Oct;140(4):549-567. doi: 10.1007/s00401-020-02187-x. Epub 2020 Jul 11. Acta Neuropathol. 2020. PMID: 32651669 Free PMC article.
NF-κB inducing kinase (NIK) is an essential post-transcriptional regulator of T-cell activation affecting F-actin dynamics and TCR signaling.
Lacher SM, Thurm C, Distler U, Mohebiany AN, Israel N, Kitic M, Ebering A, Tang Y, Klein M, Wabnitz GH, Wanke F, Samstag Y, Bopp T, Kurschus FC, Simeoni L, Tenzer S, Waisman A. Lacher SM, et al. Among authors: kitic m. J Autoimmun. 2018 Nov;94:110-121. doi: 10.1016/j.jaut.2018.07.017. Epub 2018 Jul 29. J Autoimmun. 2018. PMID: 30061013