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Cyclosporin A decreases apolipoprotein E secretion from human macrophages via a protein phosphatase 2B-dependent and ATP-binding cassette transporter A1 (ABCA1)-independent pathway.
Kockx M, Guo DL, Traini M, Gaus K, Kay J, Wimmer-Kleikamp S, Rentero C, Burnett JR, Le Goff W, Van Eck M, Stow JL, Jessup W, Kritharides L. Kockx M, et al. Among authors: traini m. J Biol Chem. 2009 Sep 4;284(36):24144-54. doi: 10.1074/jbc.M109.032615. Epub 2009 Jul 9. J Biol Chem. 2009. PMID: 19589783 Free PMC article.
Human macrophage cathepsin B-mediated C-terminal cleavage of apolipoprotein A-I at Ser228 severely impairs antiatherogenic capacity.
Dinnes DL, White MY, Kockx M, Traini M, Hsieh V, Kim MJ, Hou L, Jessup W, Rye KA, Thaysen-Andersen M, Cordwell SJ, Kritharides L. Dinnes DL, et al. Among authors: traini m. FASEB J. 2016 Dec;30(12):4239-4255. doi: 10.1096/fj.201600508R. Epub 2016 Sep 14. FASEB J. 2016. PMID: 27630170
Cleavage at Ser(228) is a novel, functionally important post-translational modification of apoA-I mediated by HMDMs that limits the antiatherogenic properties of apoA-I.-Dinnes, D. L. M., White, M. Y., Kockx, M., Traini, M., Hsieh, V., Kim, M …
Cleavage at Ser(228) is a novel, functionally important post-translational modification of apoA-I mediated by HMDMs that limits the antiathe …
Lipids grease the wheels of the immune system.
Traini M, Kritharides L. Traini M, et al. Curr Opin Lipidol. 2017 Dec;28(6):516-517. doi: 10.1097/MOL.0000000000000464. Curr Opin Lipidol. 2017. PMID: 29095364 No abstract available.
45 results