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Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3.
Guryanova OA, Wu Q, Cheng L, Lathia JD, Huang Z, Yang J, MacSwords J, Eyler CE, McLendon RE, Heddleston JM, Shou W, Hambardzumyan D, Lee J, Hjelmeland AB, Sloan AE, Bredel M, Stark GR, Rich JN, Bao S. Guryanova OA, et al. Among authors: bredel m. Cancer Cell. 2011 Apr 12;19(4):498-511. doi: 10.1016/j.ccr.2011.03.004. Cancer Cell. 2011. PMID: 21481791 Free PMC article.
Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2.
Eyler CE, Wu Q, Yan K, MacSwords JM, Chandler-Militello D, Misuraca KL, Lathia JD, Forrester MT, Lee J, Stamler JS, Goldman SA, Bredel M, McLendon RE, Sloan AE, Hjelmeland AB, Rich JN. Eyler CE, et al. Among authors: bredel m. Cell. 2011 Jul 8;146(1):53-66. doi: 10.1016/j.cell.2011.06.006. Cell. 2011. PMID: 21729780 Free PMC article.
Laminin alpha 2 enables glioblastoma stem cell growth.
Lathia JD, Li M, Hall PE, Gallagher J, Hale JS, Wu Q, Venere M, Levy E, Rani MR, Huang P, Bae E, Selfridge J, Cheng L, Guvenc H, McLendon RE, Nakano I, Sloan AE, Phillips HS, Lai A, Gladson CL, Bredel M, Bao S, Hjelmeland AB, Rich JN. Lathia JD, et al. Among authors: bredel m. Ann Neurol. 2012 Nov;72(5):766-78. doi: 10.1002/ana.23674. Ann Neurol. 2012. PMID: 23280793 Free PMC article.
Macropinocytosis of Bevacizumab by Glioblastoma Cells in the Perivascular Niche Affects their Survival.
Müller-Greven G, Carlin CR, Burgett ME, Ahluwalia MS, Lauko A, Nowacki AS, Herting CJ, Qadan MA, Bredel M, Toms SA, Lathia JD, Hambardzumyan D, Sarkaria JN, Hamerlik P, Gladson CL. Müller-Greven G, et al. Among authors: bredel m. Clin Cancer Res. 2017 Nov 15;23(22):7059-7071. doi: 10.1158/1078-0432.CCR-17-0249. Epub 2017 Sep 14. Clin Cancer Res. 2017. PMID: 28912141 Free PMC article.
Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion.
Venkatesh HS, Johung TB, Caretti V, Noll A, Tang Y, Nagaraja S, Gibson EM, Mount CW, Polepalli J, Mitra SS, Woo PJ, Malenka RC, Vogel H, Bredel M, Mallick P, Monje M. Venkatesh HS, et al. Among authors: bredel m. Cell. 2015 May 7;161(4):803-16. doi: 10.1016/j.cell.2015.04.012. Epub 2015 Apr 23. Cell. 2015. PMID: 25913192 Free PMC article.
Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.
Ferrarese R, Harsh GR 4th, Yadav AK, Bug E, Maticzka D, Reichardt W, Dombrowski SM, Miller TE, Masilamani AP, Dai F, Kim H, Hadler M, Scholtens DM, Yu IL, Beck J, Srinivasasainagendra V, Costa F, Baxan N, Pfeifer D, von Elverfeldt D, Backofen R, Weyerbrock A, Duarte CW, He X, Prinz M, Chandler JP, Vogel H, Chakravarti A, Rich JN, Carro MS, Bredel M. Ferrarese R, et al. Among authors: bredel m. J Clin Invest. 2014 Jul;124(7):2861-76. doi: 10.1172/JCI68836. Epub 2014 May 27. J Clin Invest. 2014. PMID: 24865424 Free PMC article.
CHD5 is a tumor suppressor at human 1p36.
Bagchi A, Papazoglu C, Wu Y, Capurso D, Brodt M, Francis D, Bredel M, Vogel H, Mills AA. Bagchi A, et al. Among authors: bredel m. Cell. 2007 Feb 9;128(3):459-75. doi: 10.1016/j.cell.2006.11.052. Cell. 2007. PMID: 17289567 Free article.
Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression.
Fedele V, Dai F, Masilamani AP, Heiland DH, Kling E, Gätjens-Sanchez AM, Ferrarese R, Platania L, Soroush D, Kim H, Nelander S, Weyerbrock A, Prinz M, Califano A, Iavarone A, Bredel M, Carro MS. Fedele V, et al. Among authors: bredel m. Mol Cancer Res. 2017 Aug;15(8):998-1011. doi: 10.1158/1541-7786.MCR-16-0494. Epub 2017 May 16. Mol Cancer Res. 2017. PMID: 28512252 Free PMC article.
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