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The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol.
Billon-Galés A, Fontaine C, Filipe C, Douin-Echinard V, Fouque MJ, Flouriot G, Gourdy P, Lenfant F, Laurell H, Krust A, Chambon P, Arnal JF. Billon-Galés A, et al. Among authors: fontaine c. Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):2053-8. doi: 10.1073/pnas.0808742106. Epub 2009 Feb 2. Proc Natl Acad Sci U S A. 2009. PMID: 19188600 Free PMC article.
Estrogen receptor alpha expression in both endothelium and hematopoietic cells is required for the accelerative effect of estradiol on reendothelialization.
Toutain CE, Filipe C, Billon A, Fontaine C, Brouchet L, Guéry JC, Gourdy P, Arnal JF, Lenfant F. Toutain CE, et al. Among authors: fontaine c. Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1543-50. doi: 10.1161/ATVBAHA.109.192849. Epub 2009 Jul 16. Arterioscler Thromb Vasc Biol. 2009. PMID: 19608969
Endothelial estrogen receptor-alpha plays a crucial role in the atheroprotective action of 17beta-estradiol in low-density lipoprotein receptor-deficient mice.
Billon-Galés A, Fontaine C, Douin-Echinard V, Delpy L, Berges H, Calippe B, Lenfant F, Laurell H, Guéry JC, Gourdy P, Arnal JF. Billon-Galés A, et al. Among authors: fontaine c. Circulation. 2009 Dec 22;120(25):2567-76. doi: 10.1161/CIRCULATIONAHA.109.898445. Epub 2009 Dec 7. Circulation. 2009. PMID: 19996016
Estrogen receptors and endothelium.
Arnal JF, Fontaine C, Billon-Galés A, Favre J, Laurell H, Lenfant F, Gourdy P. Arnal JF, et al. Among authors: fontaine c. Arterioscler Thromb Vasc Biol. 2010 Aug;30(8):1506-12. doi: 10.1161/ATVBAHA.109.191221. Arterioscler Thromb Vasc Biol. 2010. PMID: 20631350 Review.
Activation function 2 (AF2) of estrogen receptor-alpha is required for the atheroprotective action of estradiol but not to accelerate endothelial healing.
Billon-Galés A, Krust A, Fontaine C, Abot A, Flouriot G, Toutain C, Berges H, Gadeau AP, Lenfant F, Gourdy P, Chambon P, Arnal JF. Billon-Galés A, et al. Among authors: fontaine c. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13311-6. doi: 10.1073/pnas.1105632108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788522 Free PMC article.
648 results