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474 results

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Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β'-site increases Aβ generation.
Zhou L, Brouwers N, Benilova I, Vandersteen A, Mercken M, Van Laere K, Van Damme P, Demedts D, Van Leuven F, Sleegers K, Broersen K, Van Broeckhoven C, Vandenberghe R, De Strooper B. Zhou L, et al. Among authors: van laere k, van leuven f, van damme p, van broeckhoven c. EMBO Mol Med. 2011 May;3(5):291-302. doi: 10.1002/emmm.201100138. Epub 2011 Apr 15. EMBO Mol Med. 2011. PMID: 21500352 Free PMC article.
Alzheimer dementia caused by a novel mutation located in the APP C-terminal intracytosolic fragment.
Theuns J, Marjaux E, Vandenbulcke M, Van Laere K, Kumar-Singh S, Bormans G, Brouwers N, Van den Broeck M, Vennekens K, Corsmit E, Cruts M, De Strooper B, Van Broeckhoven C, Vandenberghe R. Theuns J, et al. Among authors: van den broeck m, van laere k, van broeckhoven c. Hum Mutat. 2006 Sep;27(9):888-96. doi: 10.1002/humu.20402. Hum Mutat. 2006. PMID: 16917905
Abeta amyloid deposition in the language system and how the brain responds.
Nelissen N, Vandenbulcke M, Fannes K, Verbruggen A, Peeters R, Dupont P, Van Laere K, Bormans G, Vandenberghe R. Nelissen N, et al. Among authors: van laere k. Brain. 2007 Aug;130(Pt 8):2055-69. doi: 10.1093/brain/awm133. Epub 2007 Jun 24. Brain. 2007. PMID: 17586869
Synthesis of 18F-labelled 2-(4'-fluorophenyl)-1,3-benzothiazole and evaluation as amyloid imaging agent in comparison with [11C]PIB.
Serdons K, Verduyckt T, Vanderghinste D, Cleynhens J, Borghgraef P, Vermaelen P, Terwinghe C, Van Leuven F, Van Laere K, Kung H, Bormans G, Verbruggen A. Serdons K, et al. Among authors: van leuven f, van laere k. Bioorg Med Chem Lett. 2009 Feb 1;19(3):602-5. doi: 10.1016/j.bmcl.2008.12.069. Epub 2008 Dec 24. Bioorg Med Chem Lett. 2009. PMID: 19147351
18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial.
Vandenberghe R, Van Laere K, Ivanoiu A, Salmon E, Bastin C, Triau E, Hasselbalch S, Law I, Andersen A, Korner A, Minthon L, Garraux G, Nelissen N, Bormans G, Buckley C, Owenius R, Thurfjell L, Farrar G, Brooks DJ. Vandenberghe R, et al. Among authors: van laere k. Ann Neurol. 2010 Sep;68(3):319-29. doi: 10.1002/ana.22068. Ann Neurol. 2010. PMID: 20687209 Clinical Trial.
474 results