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Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics.
Martinez-Outschoorn UE, Prisco M, Ertel A, Tsirigos A, Lin Z, Pavlides S, Wang C, Flomenberg N, Knudsen ES, Howell A, Pestell RG, Sotgia F, Lisanti MP. Martinez-Outschoorn UE, et al. Among authors: pestell rg. Cell Cycle. 2011 Apr 15;10(8):1271-86. doi: 10.4161/cc.10.8.15330. Cell Cycle. 2011. PMID: 21512313 Free PMC article.
Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress.
Volonté D, Galbiati F, Pestell RG, Lisanti MP. Volonté D, et al. Among authors: pestell rg. J Biol Chem. 2001 Mar 16;276(11):8094-103. doi: 10.1074/jbc.M009245200. Epub 2000 Nov 27. J Biol Chem. 2001. PMID: 11094059 Free article.
Acetylation in hormone signaling and the cell cycle.
Fu M, Wang C, Wang J, Zafonte BT, Lisanti MP, Pestell RG. Fu M, et al. Among authors: pestell rg. Cytokine Growth Factor Rev. 2002 Jun;13(3):259-76. doi: 10.1016/s1359-6101(02)00003-5. Cytokine Growth Factor Rev. 2002. PMID: 12486878 Review.
494 results