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LSD1 demethylates histone and non-histone proteins.
Nicholson TB, Chen T. Nicholson TB, et al. Epigenetics. 2009 Apr 1;4(3):129-32. doi: 10.4161/epi.4.3.8443. Epub 2009 Apr 14. Epigenetics. 2009. PMID: 19395867 Free article.
Retraction: Defective heart development in hypomorphic LSD1 mice.
Nicholson TB, Su H, Hevi S, Wang J, Bajko J, Li M, Valdez R, Loureiro J, Cheng X, Li E, Kinzel B, Labow M, Chen T. Nicholson TB, et al. Cell Res. 2012 Apr 10. doi: 10.1038/cr.2012.60. Online ahead of print. Cell Res. 2012. PMID: 22491473 No abstract available.
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Dowdle WE, Nyfeler B, Nagel J, Elling RA, Liu S, Triantafellow E, Menon S, Wang Z, Honda A, Pardee G, Cantwell J, Luu C, Cornella-Taracido I, Harrington E, Fekkes P, Lei H, Fang Q, Digan ME, Burdick D, Powers AF, Helliwell SB, D'Aquin S, Bastien J, Wang H, Wiederschain D, Kuerth J, Bergman P, Schwalb D, Thomas J, Ugwonali S, Harbinski F, Tallarico J, Wilson CJ, Myer VE, Porter JA, Bussiere DE, Finan PM, Labow MA, Mao X, Hamann LG, Manning BD, Valdez RA, Nicholson T, Schirle M, Knapp MS, Keaney EP, Murphy LO. Dowdle WE, et al. Among authors: nicholson t. Nat Cell Biol. 2014 Nov;16(11):1069-79. doi: 10.1038/ncb3053. Epub 2014 Oct 19. Nat Cell Biol. 2014. PMID: 25327288
Lysine-specific demethylase-2 is distinctively involved in brown and beige adipogenic differentiation.
Takase R, Hino S, Nagaoka K, Anan K, Kohrogi K, Araki H, Hino Y, Sakamoto A, Nicholson TB, Chen T, Nakao M. Takase R, et al. Among authors: nicholson tb. FASEB J. 2019 Apr;33(4):5300-5311. doi: 10.1096/fj.201801422RR. Epub 2019 Jan 25. FASEB J. 2019. PMID: 30681884 Free PMC article.
-Takase, R., Hino, S., Nagaoka, K., Anan, K., Kohrogi, K., Araki, H., Hino, Y., Sakamoto, A., Nicholson, T. B., Chen, T., Nakao, M. Lysine-specific demethylase-2 is distinctively involved in brown and beige adipogenic differentiation....
-Takase, R., Hino, S., Nagaoka, K., Anan, K., Kohrogi, K., Araki, H., Hino, Y., Sakamoto, A., Nicholson, T. B., Chen, T
722 results