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Construction of drug screening cell model and application to new compounds inhibiting FITC-fibrinogen binding to CHO cells expressing human alphaIIbbeta3.
Yang J, Yao J, Chen J, Wang XN, Zhu TY, Chen LL, Chu P. Yang J, et al. Eur J Pharmacol. 2009 Sep 15;618(1-3):1-8. doi: 10.1016/j.ejphar.2009.07.011. Epub 2009 Jul 17. Eur J Pharmacol. 2009. PMID: 19619528
To identify potential candidates for antiplatelet drugs, human alphaIIbbeta3 (GPIIb/IIIa) was expressed in Chinese hamster ovary (CHO) cells, which was validated by tetrapeptide RGDS (Arg-Gly-Asp-Ser) with IC(50) of 0.057 mM, supported by Basani's results [Basani, R. B., French, …
To identify potential candidates for antiplatelet drugs, human alphaIIbbeta3 (GPIIb/IIIa) was expressed in Chinese hamster ovary (CHO) cells …
Ursolic acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in non-small-cell lung carcinoma harbouring EGFR T790M mutations.
Yang K, Chen Y, Zhou J, Ma L, Shan Y, Cheng X, Wang Y, Zhang Z, Ji X, Chen L, Dai H, Zhu B, Li C, Tao Z, Hu X, Yin W. Yang K, et al. Among authors: chen l, chen y. Br J Pharmacol. 2019 Dec;176(24):4609-4624. doi: 10.1111/bph.14793. Epub 2019 Dec 26. Br J Pharmacol. 2019. PMID: 31322286 Free PMC article.
Evaluating the accessibility of essential medicines in China.
Xi X, Chen P, Yang F, Yang Y, Chen L, Mao N. Xi X, et al. Among authors: chen l, chen p. J Med Econ. 2018 Aug;21(8):784-792. doi: 10.1080/13696998.2018.1474744. Epub 2018 Jun 11. J Med Econ. 2018. PMID: 29741406 Free article.
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