Gough WH - Search Results

1

Open innovation for phenotypic drug discovery: The PD2 assay panel.

Lee JA, Chu S, Willard FS, Cox KL, Sells Galvin RJ, Peery RB, Oliver SE, Oler J, Meredith TD, Heidler SA, Gough WH, Husain S, Palkowitz AD, Moxham CM. Lee JA, et al. Among authors: gough wh. J Biomol Screen. 2011 Jul;16(6):588-602. doi: 10.1177/1087057111405379. Epub 2011 Apr 26. J Biomol Screen. 2011. PMID: 21521801

2

A quantitative, facile, and high-throughput image-based cell migration method is a robust alternative to the scratch assay.

Gough W, Hulkower KI, Lynch R, McGlynn P, Uhlik M, Yan L, Lee JA. Gough W, et al. J Biomol Screen. 2011 Feb;16(2):155-63. doi: 10.1177/1087057110393340. J Biomol Screen. 2011. PMID: 21297103

3

An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors.

Falcon BL, Swearingen M, Gough WH, Lee L, Foreman R, Uhlik M, Hanson JC, Lee JA, McClure DB, Chintharlapalli S. Falcon BL, et al. Among authors: gough wh. PLoS One. 2014 Sep 11;9(9):e106901. doi: 10.1371/journal.pone.0106901. eCollection 2014. PLoS One. 2014. PMID: 25210890 Free PMC article.

4

Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT₁ F receptor agonists: Evolution from bicyclic to monocyclic cores.

Zhang D, Blanco MJ, Ying BP, Kohlman D, Liang SX, Victor F, Chen Q, Krushinski J, Filla SA, Hudziak KJ, Mathes BM, Cohen MP, Zacherl D, Nelson DL, Wainscott DB, Nutter SE, Gough WH, Schaus JM, Xu YC. Zhang D, et al. Among authors: gough wh. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4337-41. doi: 10.1016/j.bmcl.2015.07.042. Epub 2015 Jul 22. Bioorg Med Chem Lett. 2015. PMID: 26271587

5

Identification of LY2510924, a novel cyclic peptide CXCR4 antagonist that exhibits antitumor activities in solid tumor and breast cancer metastatic models.

Peng SB, Zhang X, Paul D, Kays LM, Gough W, Stewart J, Uhlik MT, Chen Q, Hui YH, Zamek-Gliszczynski MJ, Wijsman JA, Credille KM, Yan LZ. Peng SB, et al. Mol Cancer Ther. 2015 Feb;14(2):480-90. doi: 10.1158/1535-7163.MCT-14-0850. Epub 2014 Dec 12. Mol Cancer Ther. 2015. PMID: 25504752

6

Defining Target Engagement Required for Efficacy In Vivo at the Retinoic Acid Receptor-Related Orphan Receptor C2 (RORγt).

Lugar CW, Clarke CA, Morphy R, Rudyk H, Sapmaz S, Stites RE, Vaught GM, Furness K, Broughton HB, Durst GL, Clawson DK, Stout SL, Guo SY, Durbin JD, Stayrook KR, Edmondson DD, Kikly K, New NE, Bina HA, Chambers MG, Shetler P, Chang WY, Chang VC, Barr R, Gough WH, Steele JP, Getman B, Patel N, Mathes BM, Richardson TI. Lugar CW, et al. Among authors: gough wh. J Med Chem. 2021 May 13;64(9):5470-5484. doi: 10.1021/acs.jmedchem.0c01918. Epub 2021 Apr 14. J Med Chem. 2021. PMID: 33852312

7

Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists.

Zhang D, Kohlman D, Krushinski J, Liang S, Ying BP, Reilly JE, Dinn SR, Wainscott DB, Nutter S, Gough W, Nelson DL, Schaus JM, Xu YC. Zhang D, et al. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6011-6. doi: 10.1016/j.bmcl.2004.09.079. Bioorg Med Chem Lett. 2004. PMID: 15546719

8

Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists.

Mathes BM, Hudziak KJ, Schaus JM, Xu YC, Nelson DL, Wainscott DB, Nutter SE, Gough WH, Branchek TA, Zgombick JM, Filla SA. Mathes BM, et al. Among authors: gough wh. Bioorg Med Chem Lett. 2004 Jan 5;14(1):167-70. doi: 10.1016/j.bmcl.2003.09.091. Bioorg Med Chem Lett. 2004. PMID: 14684321

9

cDNA cloning and characterization of a new human microsomal NAD+-dependent dehydrogenase that oxidizes all-trans-retinol and 3alpha-hydroxysteroids.

Gough WH, VanOoteghem S, Sint T, Kedishvili NY. Gough WH, et al. J Biol Chem. 1998 Jul 31;273(31):19778-85. doi: 10.1074/jbc.273.31.19778. J Biol Chem. 1998. PMID: 9677409 Free article.

10

cDNA sequence and catalytic properties of a chick embryo alcohol dehydrogenase that oxidizes retinol and 3beta,5alpha-hydroxysteroids.

Kedishvili NY, Gough WH, Chernoff EA, Hurley TD, Stone CL, Bowman KD, Popov KM, Bosron WF, Li TK. Kedishvili NY, et al. Among authors: gough wh. J Biol Chem. 1997 Mar 14;272(11):7494-500. doi: 10.1074/jbc.272.11.7494. J Biol Chem. 1997. PMID: 9054452 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

15 results

Search Page

Filters