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Cardiovascular mortality in chronic kidney disease patients undergoing percutaneous coronary intervention is mainly related to impaired P2Y12 inhibition by clopidogrel.
Morel O, El Ghannudi S, Jesel L, Radulescu B, Meyer N, Wiesel ML, Caillard S, Campia U, Moulin B, Gachet C, Ohlmann P. Morel O, et al. Among authors: gachet c. J Am Coll Cardiol. 2011 Jan 25;57(4):399-408. doi: 10.1016/j.jacc.2010.09.032. J Am Coll Cardiol. 2011. PMID: 21251579 Free article.
The extent of P2Y12 inhibition by clopidogrel in diabetes mellitus patients with acute coronary syndrome is not related to glycaemic control: roles of white blood cell count and body weight.
Morel O, El Ghannudi S, Hess S, Reydel A, Crimizade U, Jesel L, Radulescu B, Wiesel ML, Gachet C, Ohlmann P. Morel O, et al. Among authors: gachet c. Thromb Haemost. 2012 Aug;108(2):338-48. doi: 10.1160/TH11-12-0876. Epub 2012 Jun 28. Thromb Haemost. 2012. PMID: 22740070
In Vitro Binding of [³H]PSB-0413 to P2Y₁₂ Receptors.
Dupuis A, Heim V, Ohlmann P, Gachet C. Dupuis A, et al. Among authors: gachet c. Curr Protoc Pharmacol. 2015 Dec 8;71:1.35.1-1.35.19. doi: 10.1002/0471141755.ph0135s71. Curr Protoc Pharmacol. 2015. PMID: 26646192
Quantification of recombinant and platelet P2Y(1) receptors utilizing a [(125)I]-labeled high-affinity antagonist 2-iodo-N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate ([(125)I]MRS2500).
Ohlmann P, de Castro S, Brown GG Jr, Gachet C, Jacobson KA, Harden TK. Ohlmann P, et al. Among authors: gachet c. Pharmacol Res. 2010 Oct;62(4):344-51. doi: 10.1016/j.phrs.2010.05.007. Epub 2010 Jun 4. Pharmacol Res. 2010. PMID: 20594939 Free PMC article.
337 results