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Page 1
Dissociable hindbrain GLP1R circuits for satiety and aversion.
Huang KP, Acosta AA, Ghidewon MY, McKnight AD, Almeida MS, Nyema NT, Hanchak ND, Patel N, Gbenou YSK, Adriaenssens AE, Bolding KA, Alhadeff AL. Huang KP, et al. Among authors: adriaenssens ae. Nature. 2024 Aug;632(8025):585-593. doi: 10.1038/s41586-024-07685-6. Epub 2024 Jul 10. Nature. 2024. PMID: 38987598
Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding.
Adriaenssens A, Broichhagen J, de Bray A, Ast J, Hasib A, Jones B, Tomas A, Burgos NF, Woodward O, Lewis J, O'Flaherty E, El K, Cui C, Harada N, Inagaki N, Campbell J, Brierley D, Hodson DJ, Samms R, Gribble F, Reimann F. Adriaenssens A, et al. JCI Insight. 2023 May 22;8(10):e164921. doi: 10.1172/jci.insight.164921. JCI Insight. 2023. PMID: 37212283 Free PMC article.
Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice.
Lewis JE, Woodward OR, Nuzzaci D, Smith CA, Adriaenssens AE, Billing L, Brighton C, Phillips BU, Tadross JA, Kinston SJ, Ciabatti E, Göttgens B, Tripodi M, Hornigold D, Baker D, Gribble FM, Reimann F. Lewis JE, et al. Among authors: adriaenssens ae. Mol Metab. 2022 Dec;66:101604. doi: 10.1016/j.molmet.2022.101604. Epub 2022 Sep 30. Mol Metab. 2022. PMID: 36184065 Free PMC article.
A comparative transcriptomic analysis of glucagon-like peptide-1 receptor- and glucose-dependent insulinotropic polypeptide receptor-expressing cells in the hypothalamus.
Smith C, Patterson-Cross R, Woodward O, Lewis J, Chiarugi D, Merkle F, Gribble F, Reimann F, Adriaenssens A. Smith C, et al. Among authors: adriaenssens a. Appetite. 2022 Jul 1;174:106022. doi: 10.1016/j.appet.2022.106022. Epub 2022 Apr 14. Appetite. 2022. PMID: 35430298 Free PMC article.
The core clock gene, Bmal1, and its downstream target, the SNARE regulatory protein secretagogin, are necessary for circadian secretion of glucagon-like peptide-1.
Biancolin AD, Martchenko A, Mitova E, Gurges P, Michalchyshyn E, Chalmers JA, Doria A, Mychaleckyj JC, Adriaenssens AE, Reimann F, Gribble FM, Gil-Lozano M, Cox BJ, Brubaker PL. Biancolin AD, et al. Among authors: adriaenssens ae. Mol Metab. 2020 Jan;31:124-137. doi: 10.1016/j.molmet.2019.11.004. Epub 2019 Nov 21. Mol Metab. 2020. PMID: 31918914 Free PMC article.
24 results