Perrakis A - Search Results

1

Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression.

Pefani DE, Dimaki M, Spella M, Karantzelis N, Mitsiki E, Kyrousi C, Symeonidou IE, Perrakis A, Taraviras S, Lygerou Z. Pefani DE, et al. Among authors: perrakis a. J Biol Chem. 2011 Jul 1;286(26):23234-46. doi: 10.1074/jbc.M110.207688. Epub 2011 May 4. J Biol Chem. 2011. PMID: 21543332 Free PMC article.

2

The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing.

Caillat C, Pefani DE, Gillespie PJ, Taraviras S, Blow JJ, Lygerou Z, Perrakis A. Caillat C, et al. Among authors: perrakis a. J Biol Chem. 2013 Nov 1;288(44):31624-34. doi: 10.1074/jbc.M113.491928. Epub 2013 Sep 24. J Biol Chem. 2013. PMID: 24064211 Free PMC article.

3

The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins.

Caillat C, Fish A, Pefani DE, Taraviras S, Lygerou Z, Perrakis A. Caillat C, et al. Among authors: perrakis a. Acta Crystallogr D Biol Crystallogr. 2015 Nov;71(Pt 11):2278-86. doi: 10.1107/S1399004715016892. Epub 2015 Oct 31. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26527144 Free PMC article.

4

Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells.

Karantzelis N, Petropoulos M, De Marco V, Egan DA, Fish A, Christodoulou E, Will DW, Lewis JD, Perrakis A, Lygerou Z, Taraviras S. Karantzelis N, et al. Among authors: perrakis a. Front Pharmacol. 2022 Apr 25;13:860682. doi: 10.3389/fphar.2022.860682. eCollection 2022. Front Pharmacol. 2022. PMID: 35548337 Free PMC article.

5

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing.

De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A. De Marco V, et al. Among authors: perrakis a. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19807-12. doi: 10.1073/pnas.0905281106. Epub 2009 Nov 11. Proc Natl Acad Sci U S A. 2009. PMID: 19906994 Free PMC article.

6

Direct binding of Cdt2 to PCNA is important for targeting the CRL4^Cdt2 E3 ligase activity to Cdt1.

Hayashi A, Giakoumakis NN, Heidebrecht T, Ishii T, Panagopoulos A, Caillat C, Takahara M, Hibbert RG, Suenaga N, Stadnik-Spiewak M, Takahashi T, Shiomi Y, Taraviras S, von Castelmur E, Lygerou Z, Perrakis A, Nishitani H. Hayashi A, et al. Among authors: perrakis a. Life Sci Alliance. 2018 Dec 31;1(6):e201800238. doi: 10.26508/lsa.201800238. eCollection 2018 Dec. Life Sci Alliance. 2018. PMID: 30623174 Free PMC article.

7

ProteinCCD: enabling the design of protein truncation constructs for expression and crystallization experiments.

Mooij WT, Mitsiki E, Perrakis A. Mooij WT, et al. Among authors: perrakis a. Nucleic Acids Res. 2009 Jul;37(Web Server issue):W402-5. doi: 10.1093/nar/gkp256. Epub 2009 Apr 24. Nucleic Acids Res. 2009. PMID: 19395596 Free PMC article.

8

Lysophosphatidic acid produced by autotaxin acts as an allosteric modulator of its catalytic efficiency.

Salgado-Polo F, Fish A, Matsoukas MT, Heidebrecht T, Keune WJ, Perrakis A. Salgado-Polo F, et al. Among authors: perrakis a. J Biol Chem. 2018 Sep 14;293(37):14312-14327. doi: 10.1074/jbc.RA118.004450. Epub 2018 Jul 19. J Biol Chem. 2018. PMID: 30026231 Free PMC article.

9

Posttranslational modification of microtubules by the MATCAP detyrosinase.

Landskron L, Bak J, Adamopoulos A, Kaplani K, Moraiti M, van den Hengel LG, Song JY, Bleijerveld OB, Nieuwenhuis J, Heidebrecht T, Henneman L, Moutin MJ, Barisic M, Taraviras S, Perrakis A, Brummelkamp TR. Landskron L, et al. Among authors: perrakis a. Science. 2022 May 20;376(6595):eabn6020. doi: 10.1126/science.abn6020. Epub 2022 May 20. Science. 2022. PMID: 35482892

10

The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans.

Houben AJ, van Wijk XM, van Meeteren LA, van Zeijl L, van de Westerlo EM, Hausmann J, Fish A, Perrakis A, van Kuppevelt TH, Moolenaar WH. Houben AJ, et al. Among authors: perrakis a. J Biol Chem. 2013 Jan 4;288(1):510-9. doi: 10.1074/jbc.M112.358416. Epub 2012 Nov 13. J Biol Chem. 2013. PMID: 23150666 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

250 results

Search Page

Filters