Lee PL - Search Results

1

Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage.

Wu Z, Lee ST, Qiao Y, Li Z, Lee PL, Lee YJ, Jiang X, Tan J, Aau M, Lim CZ, Yu Q. Wu Z, et al. Among authors: lee pl, lee st, lee yj. Cell Death Differ. 2011 Nov;18(11):1771-9. doi: 10.1038/cdd.2011.48. Epub 2011 May 6. Cell Death Differ. 2011. PMID: 21546904 Free PMC article.

2

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.

Tan J, Yang X, Zhuang L, Jiang X, Chen W, Lee PL, Karuturi RK, Tan PB, Liu ET, Yu Q. Tan J, et al. Among authors: lee pl. Genes Dev. 2007 May 1;21(9):1050-63. doi: 10.1101/gad.1524107. Epub 2007 Apr 16. Genes Dev. 2007. PMID: 17437993 Free PMC article.

3

Ribosomal protein S27-like, a p53-inducible modulator of cell fate in response to genotoxic stress.

Li J, Tan J, Zhuang L, Banerjee B, Yang X, Chau JF, Lee PL, Hande MP, Li B, Yu Q. Li J, et al. Among authors: lee pl. Cancer Res. 2007 Dec 1;67(23):11317-26. doi: 10.1158/0008-5472.CAN-07-1088. Cancer Res. 2007. PMID: 18056458

4

DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.

Jiang X, Tan J, Li J, Kivimäe S, Yang X, Zhuang L, Lee PL, Chan MT, Stanton LW, Liu ET, Cheyette BN, Yu Q. Jiang X, et al. Among authors: lee pl. Cancer Cell. 2008 Jun;13(6):529-41. doi: 10.1016/j.ccr.2008.04.019. Cancer Cell. 2008. PMID: 18538736 Free PMC article.

5

B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer.

Tan J, Lee PL, Li Z, Jiang X, Lim YC, Hooi SC, Yu Q. Tan J, et al. Among authors: lee pl. Cancer Cell. 2010 Nov 16;18(5):459-71. doi: 10.1016/j.ccr.2010.10.021. Cancer Cell. 2010. PMID: 21075311 Free article.

6

PDK1 signaling toward PLK1-MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy.

Tan J, Li Z, Lee PL, Guan P, Aau MY, Lee ST, Feng M, Lim CZ, Lee EY, Wee ZN, Lim YC, Karuturi RK, Yu Q. Tan J, et al. Among authors: lee ey, lee pl, lee st. Cancer Discov. 2013 Oct;3(10):1156-71. doi: 10.1158/2159-8290.CD-12-0595. Epub 2013 Jul 25. Cancer Discov. 2013. PMID: 23887393

7

EZH2-mediated inactivation of IFN-γ-JAK-STAT1 signaling is an effective therapeutic target in MYC-driven prostate cancer.

Wee ZN, Li Z, Lee PL, Lee ST, Lim YP, Yu Q. Wee ZN, et al. Among authors: lee pl, lee st. Cell Rep. 2014 Jul 10;8(1):204-16. doi: 10.1016/j.celrep.2014.05.045. Epub 2014 Jun 19. Cell Rep. 2014. PMID: 24953652 Free article.

8

Integrative epigenome analysis identifies a Polycomb-targeted differentiation program as a tumor-suppressor event epigenetically inactivated in colorectal cancer.

Tan J, Yang X, Jiang X, Zhou J, Li Z, Lee PL, Li B, Robson P, Yu Q. Tan J, et al. Among authors: lee pl. Cell Death Dis. 2014 Jul 17;5(7):e1324. doi: 10.1038/cddis.2014.283. Cell Death Dis. 2014. PMID: 25032847 Free PMC article.

9

3-Deazaneplanocin A and neplanocin A analogues and their effects on apoptotic cell death.

Tam EK, Nguyen TM, Lim CZ, Lee PL, Li Z, Jiang X, Santhanakrishnan S, Tan TW, Goh YL, Wong SY, Yang H, Ong EH, Hill J, Yu Q, Chai CL. Tam EK, et al. Among authors: lee pl. ChemMedChem. 2015 Jan;10(1):173-82. doi: 10.1002/cmdc.201402315. Epub 2014 Oct 15. ChemMedChem. 2015. PMID: 25319940

10

Functional Characterization of D9, a Novel Deazaneplanocin A (DZNep) Analog, in Targeting Acute Myeloid Leukemia (AML).

Jiang X, Lim CZ, Li Z, Lee PL, Yatim SM, Guan P, Li J, Zhou J, Pan J, Chng WJ, Chai CL, Yu Q. Jiang X, et al. Among authors: lee pl. PLoS One. 2015 Apr 30;10(4):e0122983. doi: 10.1371/journal.pone.0122983. eCollection 2015. PLoS One. 2015. PMID: 25928216 Free PMC article.

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