Ernst B - Search Results

1

High affinity sialoside ligands of myelin associated glycoprotein.

Zeng Y, Rademacher C, Nycholat CM, Futakawa S, Lemme K, Ernst B, Paulson JC. Zeng Y, et al. Among authors: ernst b. Bioorg Med Chem Lett. 2011 Sep 1;21(17):5045-9. doi: 10.1016/j.bmcl.2011.04.068. Epub 2011 Apr 23. Bioorg Med Chem Lett. 2011. PMID: 21561770 Free PMC article.

2

Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction.

Tsai CY, Park WK, Weitz-Schmidt G, Ernst B, Wong CH. Tsai CY, et al. Among authors: ernst b. Bioorg Med Chem Lett. 1998 Sep 8;8(17):2333-8. doi: 10.1016/s0960-894x(98)00422-3. Bioorg Med Chem Lett. 1998. PMID: 9873537

3

Antagonists of the myelin-associated glycoprotein: a new class of tetrasaccharide mimics.

Schwizer D, Gäthje H, Kelm S, Porro M, Schwardt O, Ernst B. Schwizer D, et al. Among authors: ernst b. Bioorg Med Chem. 2006 Jul 15;14(14):4944-57. doi: 10.1016/j.bmc.2006.03.007. Epub 2006 Mar 31. Bioorg Med Chem. 2006. PMID: 16580208

4

Synthesis of sialic acid derivatives as ligands for the myelin-associated glycoprotein (MAG).

Shelke SV, Gao GP, Mesch S, Gäthje H, Kelm S, Schwardt O, Ernst B. Shelke SV, et al. Among authors: ernst b. Bioorg Med Chem. 2007 Jul 15;15(14):4951-65. doi: 10.1016/j.bmc.2007.04.038. Epub 2007 Apr 25. Bioorg Med Chem. 2007. PMID: 17507233

5

Mimetics of the tri- and tetrasaccharide epitope of GQ1balpha as myelin-associated glycoprotein (MAG) ligands.

Gao G, Smiesko M, Schwardt O, Gäthje H, Kelm S, Vedani A, Ernst B. Gao G, et al. Among authors: ernst b. Bioorg Med Chem. 2007 Dec 1;15(23):7459-69. doi: 10.1016/j.bmc.2007.07.033. Epub 2007 Aug 21. Bioorg Med Chem. 2007. PMID: 17870542

6

Examination of the biological role of the alpha(2-->6)-linked sialic acid in gangliosides binding to the myelin-associated glycoprotein (MAG).

Schwardt O, Gäthje H, Vedani A, Mesch S, Gao GP, Spreafico M, von Orelli J, Kelm S, Ernst B. Schwardt O, et al. Among authors: ernst b. J Med Chem. 2009 Feb 26;52(4):989-1004. doi: 10.1021/jm801058n. J Med Chem. 2009. PMID: 19175312

7

Low molecular weight antagonists of the myelin-associated glycoprotein: synthesis, docking, and biological evaluation.

Mesch S, Moser D, Strasser DS, Kelm A, Cutting B, Rossato G, Vedani A, Koliwer-Brandl H, Wittwer M, Rabbani S, Schwardt O, Kelm S, Ernst B. Mesch S, et al. Among authors: ernst b. J Med Chem. 2010 Feb 25;53(4):1597-615. doi: 10.1021/jm901517k. J Med Chem. 2010. PMID: 20095613

8

Kinetic and thermodynamic properties of MAG antagonists.

Mesch S, Lemme K, Koliwer-Brandl H, Strasser DS, Schwardt O, Kelm S, Ernst B. Mesch S, et al. Among authors: ernst b. Carbohydr Res. 2010 Jul 2;345(10):1348-59. doi: 10.1016/j.carres.2010.03.010. Epub 2010 Mar 16. Carbohydr Res. 2010. PMID: 20359700

9

Design, synthesis, biological evaluation, and modeling of a non-carbohydrate antagonist of the myelin-associated glycoprotein.

Schwardt O, Koliwer-Brandl H, Zimmerli R, Mesch S, Rossato G, Spreafico M, Vedani A, Kelm S, Ernst B. Schwardt O, et al. Among authors: ernst b. Bioorg Med Chem. 2010 Oct 15;18(20):7239-51. doi: 10.1016/j.bmc.2010.08.027. Epub 2010 Aug 17. Bioorg Med Chem. 2010. PMID: 20843694

10

From a library of MAG antagonists to nanomolar CD22 ligands.

Mesch S, Lemme K, Wittwer M, Koliwer-Brandl H, Schwardt O, Kelm S, Ernst B. Mesch S, et al. Among authors: ernst b. ChemMedChem. 2012 Jan 2;7(1):134-43. doi: 10.1002/cmdc.201100407. Epub 2011 Oct 11. ChemMedChem. 2012. PMID: 21990163

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