Dinsdale D - Search Results

1

BCL2/BCL-X(L) inhibition induces apoptosis, disrupts cellular calcium homeostasis, and prevents platelet activation.

Vogler M, Hamali HA, Sun XM, Bampton ET, Dinsdale D, Snowden RT, Dyer MJ, Goodall AH, Cohen GM. Vogler M, et al. Among authors: dinsdale d. Blood. 2011 Jun 30;117(26):7145-54. doi: 10.1182/blood-2011-03-344812. Epub 2011 May 11. Blood. 2011. PMID: 21562047 Free article.

2

Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells.

Baou M, Kohlhaas SL, Butterworth M, Vogler M, Dinsdale D, Walewska R, Majid A, Eldering E, Dyer MJ, Cohen GM. Baou M, et al. Among authors: dinsdale d. Haematologica. 2010 Sep;95(9):1510-8. doi: 10.3324/haematol.2010.022368. Epub 2010 Apr 7. Haematologica. 2010. PMID: 20378569 Free PMC article.

3

ABT-199 selectively inhibits BCL2 but not BCL2L1 and efficiently induces apoptosis of chronic lymphocytic leukaemic cells but not platelets.

Vogler M, Dinsdale D, Dyer MJ, Cohen GM. Vogler M, et al. Among authors: dinsdale d. Br J Haematol. 2013 Oct;163(1):139-42. doi: 10.1111/bjh.12457. Epub 2013 Jul 4. Br J Haematol. 2013. PMID: 23826785 Free article. No abstract available.

4

A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells.

Vogler M, Dinsdale D, Sun XM, Young KW, Butterworth M, Nicotera P, Dyer MJ, Cohen GM. Vogler M, et al. Among authors: dinsdale d. Cell Death Differ. 2008 May;15(5):820-30. doi: 10.1038/cdd.2008.25. Epub 2008 Feb 29. Cell Death Differ. 2008. PMID: 18309326

5

Bcl-2 inhibitors: small molecules with a big impact on cancer therapy.

Vogler M, Dinsdale D, Dyer MJ, Cohen GM. Vogler M, et al. Among authors: dinsdale d. Cell Death Differ. 2009 Mar;16(3):360-7. doi: 10.1038/cdd.2008.137. Epub 2008 Sep 19. Cell Death Differ. 2009. PMID: 18806758 Review.

6

Different forms of cell death induced by putative BCL2 inhibitors.

Vogler M, Weber K, Dinsdale D, Schmitz I, Schulze-Osthoff K, Dyer MJ, Cohen GM. Vogler M, et al. Among authors: dinsdale d. Cell Death Differ. 2009 Jul;16(7):1030-9. doi: 10.1038/cdd.2009.48. Epub 2009 Apr 24. Cell Death Differ. 2009. PMID: 19390557

7

Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis.

Varadarajan S, Tanaka K, Smalley JL, Bampton ET, Pellecchia M, Dinsdale D, Willars GB, Cohen GM. Varadarajan S, et al. Among authors: dinsdale d. PLoS One. 2013;8(2):e56603. doi: 10.1371/journal.pone.0056603. Epub 2013 Feb 15. PLoS One. 2013. PMID: 23457590 Free PMC article.

8

Sabutoclax (BI97C1) and BI112D1, putative inhibitors of MCL-1, induce mitochondrial fragmentation either upstream of or independent of apoptosis.

Varadarajan S, Butterworth M, Wei J, Pellecchia M, Dinsdale D, Cohen GM. Varadarajan S, et al. Among authors: dinsdale d. Neoplasia. 2013 May;15(5):568-78. doi: 10.1593/neo.13230. Neoplasia. 2013. PMID: 23633928 Free PMC article.

9

Characterization of apoptosis in thymocytes isolated from dexamethasone-treated rats.

Sun XM, Dinsdale D, Snowden RT, Cohen GM, Skilleter DN. Sun XM, et al. Among authors: dinsdale d. Biochem Pharmacol. 1992 Dec 1;44(11):2131-7. doi: 10.1016/0006-2952(92)90339-k. Biochem Pharmacol. 1992. PMID: 1472078

10

Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes.

Cohen GM, Sun XM, Fearnhead H, MacFarlane M, Brown DG, Snowden RT, Dinsdale D. Cohen GM, et al. Among authors: dinsdale d. J Immunol. 1994 Jul 15;153(2):507-16. J Immunol. 1994. PMID: 8021492

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