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Page 1
A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.
Klinakis A, Lobry C, Abdel-Wahab O, Oh P, Haeno H, Buonamici S, van De Walle I, Cathelin S, Trimarchi T, Araldi E, Liu C, Ibrahim S, Beran M, Zavadil J, Efstratiadis A, Taghon T, Michor F, Levine RL, Aifantis I. Klinakis A, et al. Among authors: lobry c. Nature. 2011 May 12;473(7346):230-3. doi: 10.1038/nature09999. Nature. 2011. PMID: 21562564 Free PMC article.
PHF6 mutations in adult acute myeloid leukemia.
Van Vlierberghe P, Patel J, Abdel-Wahab O, Lobry C, Hedvat CV, Balbin M, Nicolas C, Payer AR, Fernandez HF, Tallman MS, Paietta E, Melnick A, Vandenberghe P, Speleman F, Aifantis I, Cools J, Levine R, Ferrando A. Van Vlierberghe P, et al. Among authors: lobry c. Leukemia. 2011 Jan;25(1):130-4. doi: 10.1038/leu.2010.247. Epub 2010 Oct 29. Leukemia. 2011. PMID: 21030981 Free PMC article.
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D, Lobry C, Figueroa ME, Vasanthakumar A, Patel J, Zhao X, Perna F, Pandey S, Madzo J, Song C, Dai Q, He C, Ibrahim S, Beran M, Zavadil J, Nimer SD, Melnick A, Godley LA, Aifantis I, Levine RL. Moran-Crusio K, et al. Among authors: lobry c. Cancer Cell. 2011 Jul 12;20(1):11-24. doi: 10.1016/j.ccr.2011.06.001. Epub 2011 Jun 30. Cancer Cell. 2011. PMID: 21723200 Free PMC article.
T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling.
Germar K, Dose M, Konstantinou T, Zhang J, Wang H, Lobry C, Arnett KL, Blacklow SC, Aifantis I, Aster JC, Gounari F. Germar K, et al. Among authors: lobry c. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20060-5. doi: 10.1073/pnas.1110230108. Epub 2011 Nov 22. Proc Natl Acad Sci U S A. 2011. PMID: 22109558 Free PMC article.
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice.
Billiard F, Lobry C, Darrasse-Jèze G, Waite J, Liu X, Mouquet H, DaNave A, Tait M, Idoyaga J, Leboeuf M, Kyratsous CA, Burton J, Kalter J, Klinakis A, Zhang W, Thurston G, Merad M, Steinman RM, Murphy AJ, Yancopoulos GD, Aifantis I, Skokos D. Billiard F, et al. Among authors: lobry c. J Exp Med. 2012 May 7;209(5):1011-28. doi: 10.1084/jem.20111615. Epub 2012 Apr 30. J Exp Med. 2012. PMID: 22547652 Free PMC article.
Notch pathway activation targets AML-initiating cell homeostasis and differentiation.
Lobry C, Ntziachristos P, Ndiaye-Lobry D, Oh P, Cimmino L, Zhu N, Araldi E, Hu W, Freund J, Abdel-Wahab O, Ibrahim S, Skokos D, Armstrong SA, Levine RL, Park CY, Aifantis I. Lobry C, et al. J Exp Med. 2013 Feb 11;210(2):301-19. doi: 10.1084/jem.20121484. Epub 2013 Jan 28. J Exp Med. 2013. PMID: 23359070 Free PMC article.
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells.
Guy CS, Vignali KM, Temirov J, Bettini ML, Overacre AE, Smeltzer M, Zhang H, Huppa JB, Tsai YH, Lobry C, Xie J, Dempsey PJ, Crawford HC, Aifantis I, Davis MM, Vignali DA. Guy CS, et al. Among authors: lobry c. Nat Immunol. 2013 Mar;14(3):262-70. doi: 10.1038/ni.2538. Epub 2013 Feb 3. Nat Immunol. 2013. PMID: 23377202 Free PMC article.
In vivo mapping of notch pathway activity in normal and stress hematopoiesis.
Oh P, Lobry C, Gao J, Tikhonova A, Loizou E, Manet J, van Handel B, Ibrahim S, Greve J, Mikkola H, Artavanis-Tsakonas S, Aifantis I. Oh P, et al. Among authors: lobry c. Cell Stem Cell. 2013 Aug 1;13(2):190-204. doi: 10.1016/j.stem.2013.05.015. Epub 2013 Jun 20. Cell Stem Cell. 2013. PMID: 23791481 Free PMC article.
64 results