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Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcome.
Huang J, Zhang L, Greshock J, Colligon TA, Wang Y, Ward R, Katsaros D, Lassus H, Butzow R, Godwin AK, Testa JR, Nathanson KL, Gimotty PA, Coukos G, Weber BL, Degenhardt Y. Huang J, et al. Among authors: degenhardt y. Genes Chromosomes Cancer. 2011 Aug;50(8):606-18. doi: 10.1002/gcc.20883. Epub 2011 May 11. Genes Chromosomes Cancer. 2011. PMID: 21563232 Free PMC article.
Distinct MHC gene expression patterns during progression of melanoma.
Degenhardt Y, Huang J, Greshock J, Horiates G, Nathanson K, Yang X, Herlyn M, Weber B. Degenhardt Y, et al. Genes Chromosomes Cancer. 2010 Feb;49(2):144-54. doi: 10.1002/gcc.20728. Genes Chromosomes Cancer. 2010. PMID: 19862823 Free PMC article.
Molecular target class is predictive of in vitro response profile.
Greshock J, Bachman KE, Degenhardt YY, Jing J, Wen YH, Eastman S, McNeil E, Moy C, Wegrzyn R, Auger K, Hardwicke MA, Wooster R. Greshock J, et al. Among authors: degenhardt yy. Cancer Res. 2010 May 1;70(9):3677-86. doi: 10.1158/0008-5472.CAN-09-3788. Epub 2010 Apr 20. Cancer Res. 2010. PMID: 20406975
Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability.
Degenhardt Y, Greshock J, Laquerre S, Gilmartin AG, Jing J, Richter M, Zhang X, Bleam M, Halsey W, Hughes A, Moy C, Liu-Sullivan N, Powers S, Bachman K, Jackson J, Weber B, Wooster R. Degenhardt Y, et al. Mol Cancer Ther. 2010 Jul;9(7):2079-89. doi: 10.1158/1535-7163.MCT-10-0095. Epub 2010 Jun 22. Mol Cancer Ther. 2010. PMID: 20571075
Comprehensive predictive biomarker analysis for MEK inhibitor GSK1120212.
Jing J, Greshock J, Holbrook JD, Gilmartin A, Zhang X, McNeil E, Conway T, Moy C, Laquerre S, Bachman K, Wooster R, Degenhardt Y. Jing J, et al. Among authors: degenhardt y. Mol Cancer Ther. 2012 Mar;11(3):720-9. doi: 10.1158/1535-7163.MCT-11-0505. Epub 2011 Dec 14. Mol Cancer Ther. 2012. PMID: 22169769
High-content analysis of cancer genome DNA alterations.
Degenhardt YY, Wooster R, McCombie RW, Lucito R, Powers S. Degenhardt YY, et al. Curr Opin Genet Dev. 2008 Feb;18(1):68-72. doi: 10.1016/j.gde.2008.01.005. Epub 2008 Mar 12. Curr Opin Genet Dev. 2008. PMID: 18339543 Free PMC article. Review.
21 results