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EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells.
De Weer A, Van der Meulen J, Rondou P, Taghon T, Konrad TA, De Preter K, Mestdagh P, Van Maerken T, Van Roy N, Jeison M, Yaniv I, Cauwelier B, Noens L, Poirel HA, Vandenberghe P, Lambert F, De Paepe A, Sánchez MG, Odero M, Verhasselt B, Philippé J, Vandesompele J, Wieser R, Dastugue N, Van Vlierberghe P, Poppe B, Speleman F. De Weer A, et al. Among authors: de paepe a, de preter k. Br J Haematol. 2011 Aug;154(3):337-48. doi: 10.1111/j.1365-2141.2011.08737.x. Epub 2011 May 14. Br J Haematol. 2011. PMID: 21569010 Free article.
EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22.
De Weer A, Speleman F, Cauwelier B, Van Roy N, Yigit N, Verhasselt B, De Moerloose B, Benoit Y, Noens L, Selleslag D, Lippert E, Struski S, Bastard C, De Paepe A, Vandenberghe P, Hagemeijer A, Dastugue N, Poppe B; Groupe Français de Cytogénétique Hématologique (GFCH). De Weer A, et al. Among authors: de moerloose b, de paepe a. Haematologica. 2008 Dec;93(12):1903-7. doi: 10.3324/haematol.13192. Epub 2008 Sep 24. Haematologica. 2008. PMID: 18815193 Free article.
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias.
Speleman F, Cauwelier B, Dastugue N, Cools J, Verhasselt B, Poppe B, Van Roy N, Vandesompele J, Graux C, Uyttebroeck A, Boogaerts M, De Moerloose B, Benoit Y, Selleslag D, Billiet J, Robert A, Huguet F, Vandenberghe P, De Paepe A, Marynen P, Hagemeijer A. Speleman F, et al. Among authors: de moerloose b, de paepe a. Leukemia. 2005 Mar;19(3):358-66. doi: 10.1038/sj.leu.2403657. Leukemia. 2005. PMID: 15674412 Free article.
Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies.
Poppe B, Vandesompele J, Schoch C, Lindvall C, Mrozek K, Bloomfield CD, Beverloo HB, Michaux L, Dastugue N, Herens C, Yigit N, De Paepe A, Hagemeijer A, Speleman F. Poppe B, et al. Among authors: de paepe a. Blood. 2004 Jan 1;103(1):229-35. doi: 10.1182/blood-2003-06-2163. Epub 2003 Aug 28. Blood. 2004. PMID: 12946992 Free article.
501 results