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Induction of thymidine phosphorylase as a pharmacodynamic end-point in patients with advanced carcinoma treated with 5-fluorouracil, folinic acid and interferon alpha.
Braybrooke JP, Propper DJ, O'Byrne KJ, Koukourakis MI, Patterson AV, Houlbrook S, Love SD, Varcoe S, Taylor M, Ganesan TS, Talbot DC, Harris AL. Braybrooke JP, et al. Among authors: taylor m. Br J Cancer. 2000 Jul;83(2):219-24. doi: 10.1054/bjoc.2000.1230. Br J Cancer. 2000. PMID: 10901374 Free PMC article. Clinical Trial.
COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment.
Generali D, Buffa FM, Deb S, Cummings M, Reid LE, Taylor M, Andreis D, Allevi G, Ferrero G, Byrne D, Martinotti M, Bottini A, Harris AL, Lakhani SR, Fox SB. Generali D, et al. Among authors: taylor m. Br J Cancer. 2014 Jul 8;111(1):46-54. doi: 10.1038/bjc.2014.236. Epub 2014 May 29. Br J Cancer. 2014. PMID: 24874483 Free PMC article. Clinical Trial.
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