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The antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate.
Ranasinghe SR, Kramer HB, Wright C, Kessler BM, di Gleria K, Zhang Y, Gillespie GM, Blais ME, Culshaw A, Pichulik T, Simmons A, Rowland-Jones SL, McMichael AJ, Dong T. Ranasinghe SR, et al. Among authors: kramer hb. PLoS Pathog. 2011 May;7(5):e1001341. doi: 10.1371/journal.ppat.1001341. Epub 2011 May 12. PLoS Pathog. 2011. PMID: 21589893 Free PMC article.
The presence of prolines in the flanking region of an immunodominant HIV-2 gag epitope influences the quality and quantity of the epitope generated.
Jallow S, Leligdowicz A, Kramer HB, Onyango C, Cotten M, Wright C, Whittle HC, McMichael A, Dong T, Kessler BM, Rowland-Jones SL. Jallow S, et al. Among authors: kramer hb. Eur J Immunol. 2015 Aug;45(8):2232-42. doi: 10.1002/eji.201545451. Epub 2015 Jun 24. Eur J Immunol. 2015. PMID: 26018465 Free PMC article.
Correction. The presence of prolines in the flanking region of an immunodominant HIV-2 gag epitope influences the quality and quantity of the epitope generated.
Jallow S, Leligdowicz A, Kramer HB, Onyango C, Cotten M, Wright C, Whittle HC, McMichael A, Dong T, Kessler BM, Rowland-Jones SL. Jallow S, et al. Among authors: kramer hb. Eur J Immunol. 2015 Sep;45(9):2701. doi: 10.1002/eji.201570096. Eur J Immunol. 2015. PMID: 26343564 Free PMC article. No abstract available.
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