Hagen ME - Search Results

1

(+-)-(1 alpha,2 beta,3 alpha)-9-[2,3-bis(hydroxymethyl)-cyclobutyl] guanine [(+-)-BHCG or SQ 33,054]: a potent and selective inhibitor of herpesviruses.

Field AK, Tuomari AV, McGeever-Rubin B, Terry BJ, Mazina KE, Haffey ML, Hagen ME, Clark JM, Braitman A, Slusarchyk WA, et al. Field AK, et al. Among authors: hagen me. Antiviral Res. 1990 Jan;13(1):41-52. doi: 10.1016/0166-3542(90)90043-7. Antiviral Res. 1990. PMID: 2159261

2

Inhibition of herpes simplex virus type 1 DNA polymerase by [1R(1 alpha,2 beta,3 alpha)]-9-[2,3-bis(hydroxymethyl)cyclobutyl] guanine.

Terry BJ, Cianci CW, Hagen ME. Terry BJ, et al. Among authors: hagen me. Mol Pharmacol. 1991 Oct;40(4):591-6. Mol Pharmacol. 1991. PMID: 1656194

3

Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogues.

Bisacchi GS, Braitman A, Cianci CW, Clark JM, Field AK, Hagen ME, Hockstein DR, Malley MF, Mitt T, Slusarchyk WA, et al. Bisacchi GS, et al. Among authors: hagen me. J Med Chem. 1991 Apr;34(4):1415-21. doi: 10.1021/jm00108a026. J Med Chem. 1991. PMID: 1849998

4

Selective activity and cellular pharmacology of (1R-1 alpha,2 beta,3 alpha)-9-[2,3-bis(hydroxymethyl)cyclobutyl]guanine in herpesvirus-infected cells.

Yamanaka G, Tuomari AV, Hagen M, McGeever-Rubin B, Terry B, Haffey M, Bisacchi GS, Field AK. Yamanaka G, et al. Mol Pharmacol. 1991 Sep;40(3):446-53. Mol Pharmacol. 1991. PMID: 1896029

5

Broad-spectrum antiviral activity of the acyclic guanosine phosphonate (R,S)-HPMPG.

Terry BJ, Mazina KE, Tuomari AV, Haffey ML, Hagen M, Feldman A, Slusarchyk WA, Young MG, Zahler R, Field AK. Terry BJ, et al. Antiviral Res. 1988 Dec 1;10(4-5):235-51. doi: 10.1016/0166-3542(88)90034-4. Antiviral Res. 1988. PMID: 2852486

6

Biochemical studies on capped RNA primers identify a class of oligonucleotide inhibitors of the influenza virus RNA polymerase.

Chung TD, Cianci C, Hagen M, Terry B, Matthews JT, Krystal M, Colonno RJ. Chung TD, et al. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2372-6. doi: 10.1073/pnas.91.6.2372. Proc Natl Acad Sci U S A. 1994. PMID: 7510890 Free PMC article.

7

Sequence-specific binding of the influenza virus RNA polymerase to sequences located at the 5' ends of the viral RNAs.

Tiley LS, Hagen M, Matthews JT, Krystal M. Tiley LS, et al. J Virol. 1994 Aug;68(8):5108-16. doi: 10.1128/JVI.68.8.5108-5116.1994. J Virol. 1994. PMID: 8035510 Free PMC article.

8

Herpes simplex virus type 1 protease expressed in Escherichia coli exhibits autoprocessing and specific cleavage of the ICP35 assembly protein.

Deckman IC, Hagen M, McCann PJ 3rd. Deckman IC, et al. J Virol. 1992 Dec;66(12):7362-7. doi: 10.1128/JVI.66.12.7362-7367.1992. J Virol. 1992. PMID: 1331526 Free PMC article.

9

Recombinant influenza virus polymerase: requirement of both 5' and 3' viral ends for endonuclease activity.

Hagen M, Chung TD, Butcher JA, Krystal M. Hagen M, et al. J Virol. 1994 Mar;68(3):1509-15. doi: 10.1128/JVI.68.3.1509-1515.1994. J Virol. 1994. PMID: 8107213 Free PMC article.

10

The role of template-primer interactions in cleavage and initiation by the influenza virus polymerase.

Hagen M, Tiley L, Chung TD, Krystal M. Hagen M, et al. J Gen Virol. 1995 Mar;76 ( Pt 3):603-11. doi: 10.1099/0022-1317-76-3-603. J Gen Virol. 1995. PMID: 7534813

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