Walsh DM - Search Results

1

Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein.

Barry AE, Klyubin I, Mc Donald JM, Mably AJ, Farrell MA, Scott M, Walsh DM, Rowan MJ. Barry AE, et al. Among authors: walsh dm. J Neurosci. 2011 May 18;31(20):7259-63. doi: 10.1523/JNEUROSCI.6500-10.2011. J Neurosci. 2011. PMID: 21593310 Free PMC article.

2

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo.

Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rowan MJ, Selkoe DJ. Walsh DM, et al. Nature. 2002 Apr 4;416(6880):535-9. doi: 10.1038/416535a. Nature. 2002. PMID: 11932745

3

Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition.

Walsh DM, Klyubin I, Fadeeva JV, Rowan MJ, Selkoe DJ. Walsh DM, et al. Biochem Soc Trans. 2002 Aug;30(4):552-7. doi: 10.1042/bst0300552. Biochem Soc Trans. 2002. PMID: 12196135 Review.

4

Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5.

Wang Q, Walsh DM, Rowan MJ, Selkoe DJ, Anwyl R. Wang Q, et al. Among authors: walsh dm. J Neurosci. 2004 Mar 31;24(13):3370-8. doi: 10.1523/JNEUROSCI.1633-03.2004. J Neurosci. 2004. PMID: 15056716 Free PMC article.

5

Soluble Arctic amyloid beta protein inhibits hippocampal long-term potentiation in vivo.

Klyubin I, Walsh DM, Cullen WK, Fadeeva JV, Anwyl R, Selkoe DJ, Rowan MJ. Klyubin I, et al. Among authors: walsh dm. Eur J Neurosci. 2004 May;19(10):2839-46. doi: 10.1111/j.1460-9568.2004.03389.x. Eur J Neurosci. 2004. PMID: 15147317

6

Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation.

Walsh DM, Townsend M, Podlisny MB, Shankar GM, Fadeeva JV, El Agnaf O, Hartley DM, Selkoe DJ. Walsh DM, et al. J Neurosci. 2005 Mar 9;25(10):2455-62. doi: 10.1523/JNEUROSCI.4391-04.2005. J Neurosci. 2005. PMID: 15758153 Free PMC article.

7

Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo.

Klyubin I, Walsh DM, Lemere CA, Cullen WK, Shankar GM, Betts V, Spooner ET, Jiang L, Anwyl R, Selkoe DJ, Rowan MJ. Klyubin I, et al. Among authors: walsh dm. Nat Med. 2005 May;11(5):556-61. doi: 10.1038/nm1234. Epub 2005 Apr 17. Nat Med. 2005. PMID: 15834427

8

The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.

Walsh DM, Klyubin I, Shankar GM, Townsend M, Fadeeva JV, Betts V, Podlisny MB, Cleary JP, Ashe KH, Rowan MJ, Selkoe DJ. Walsh DM, et al. Biochem Soc Trans. 2005 Nov;33(Pt 5):1087-90. doi: 10.1042/BST20051087. Biochem Soc Trans. 2005. PMID: 16246051 Review.

9

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway.

Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, Sabatini BL. Shankar GM, et al. Among authors: walsh dm. J Neurosci. 2007 Mar 14;27(11):2866-75. doi: 10.1523/JNEUROSCI.4970-06.2007. J Neurosci. 2007. PMID: 17360908 Free PMC article.

10

Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization.

Klyubin I, Betts V, Welzel AT, Blennow K, Zetterberg H, Wallin A, Lemere CA, Cullen WK, Peng Y, Wisniewski T, Selkoe DJ, Anwyl R, Walsh DM, Rowan MJ. Klyubin I, et al. Among authors: walsh dm. J Neurosci. 2008 Apr 16;28(16):4231-7. doi: 10.1523/JNEUROSCI.5161-07.2008. J Neurosci. 2008. PMID: 18417702 Free PMC article.

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