Horton SJ - Search Results

1

Zinc finger protein 521 antagonizes early B-cell factor 1 and modulates the B-lymphoid differentiation of primary hematopoietic progenitors.

Mega T, Lupia M, Amodio N, Horton SJ, Mesuraca M, Pelaggi D, Agosti V, Grieco M, Chiarella E, Spina R, Moore MA, Schuringa JJ, Bond HM, Morrone G. Mega T, et al. Among authors: horton sj. Cell Cycle. 2011 Jul 1;10(13):2129-39. doi: 10.4161/cc.10.13.16045. Epub 2011 Jul 1. Cell Cycle. 2011. PMID: 21593590

2

Genetic and epigenetic alterations that drive leukemic stem cell self-renewal.

van den Boom V, Horton SJ, Schuringa JJ. van den Boom V, et al. Among authors: horton sj. J Stem Cells. 2012;7(3):155-79. J Stem Cells. 2012. PMID: 23619382 Review.

3

The AAA+ ATPase RUVBL2 is a critical mediator of MLL-AF9 oncogenesis.

Osaki H, Walf-Vorderwülbecke V, Mangolini M, Zhao L, Horton SJ, Morrone G, Schuringa JJ, de Boer J, Williams O. Osaki H, et al. Among authors: horton sj. Leukemia. 2013 Jul;27(7):1461-8. doi: 10.1038/leu.2013.42. Epub 2013 Feb 13. Leukemia. 2013. PMID: 23403462

4

BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells.

Carretta M, Brouwers-Vos AZ, Bosman M, Horton SJ, Martens JHA, Vellenga E, Schuringa JJ. Carretta M, et al. Among authors: horton sj. PLoS One. 2017 Dec 14;12(12):e0189102. doi: 10.1371/journal.pone.0189102. eCollection 2017. PLoS One. 2017. PMID: 29240787 Free PMC article.

5

MLL-AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny.

Horton SJ, Jaques J, Woolthuis C, van Dijk J, Mesuraca M, Huls G, Morrone G, Vellenga E, Schuringa JJ. Horton SJ, et al. Leukemia. 2013 Apr;27(5):1116-26. doi: 10.1038/leu.2012.343. Epub 2012 Nov 26. Leukemia. 2013. PMID: 23178754

6

The mechanism of hematopoietic progenitor cell immortalization by MLL-ENL.

Horton SJ, Williams O. Horton SJ, et al. Cell Cycle. 2006 Feb;5(4):360-2. doi: 10.4161/cc.5.4.2464. Epub 2006 Feb 15. Cell Cycle. 2006. PMID: 16479159

7

BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells.

Rizo A, Horton SJ, Olthof S, Dontje B, Ausema A, van Os R, van den Boom V, Vellenga E, de Haan G, Schuringa JJ. Rizo A, et al. Among authors: horton sj. Blood. 2010 Nov 25;116(22):4621-30. doi: 10.1182/blood-2010-02-270660. Epub 2010 Aug 19. Blood. 2010. PMID: 20724541 Free article.

8

Genetically engineered mesenchymal stromal cells produce IL-3 and TPO to further improve human scaffold-based xenograft models.

Carretta M, de Boer B, Jaques J, Antonelli A, Horton SJ, Yuan H, de Bruijn JD, Groen RWJ, Vellenga E, Schuringa JJ. Carretta M, et al. Among authors: horton sj. Exp Hematol. 2017 Jul;51:36-46. doi: 10.1016/j.exphem.2017.04.008. Epub 2017 Apr 26. Exp Hematol. 2017. PMID: 28456746 Free article.

9

Continuous MLL-ENL expression is necessary to establish a "Hox Code" and maintain immortalization of hematopoietic progenitor cells.

Horton SJ, Grier DG, McGonigle GJ, Thompson A, Morrow M, De Silva I, Moulding DA, Kioussis D, Lappin TR, Brady HJ, Williams O. Horton SJ, et al. Cancer Res. 2005 Oct 15;65(20):9245-52. doi: 10.1158/0008-5472.CAN-05-1691. Cancer Res. 2005. PMID: 16230385

10

Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors.

Horton SJ, Giotopoulos G, Yun H, Vohra S, Sheppard O, Bashford-Rogers R, Rashid M, Clipson A, Chan WI, Sasca D, Yiangou L, Osaki H, Basheer F, Gallipoli P, Burrows N, Erdem A, Sybirna A, Foerster S, Zhao W, Sustic T, Petrunkina Harrison A, Laurenti E, Okosun J, Hodson D, Wright P, Smith KG, Maxwell P, Fitzgibbon J, Du MQ, Adams DJ, Huntly BJP. Horton SJ, et al. Nat Cell Biol. 2017 Sep;19(9):1093-1104. doi: 10.1038/ncb3597. Epub 2017 Aug 21. Nat Cell Biol. 2017. PMID: 28825697 Free PMC article.

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